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trichosanthes cucumeroides/atrophy
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5 results
Trichosanthes kirilowii lectin ameliorates streptozocin-induced kidney injury via modulation of the balance between M1/M2 phenotype macrophage.
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BACKGROUND
Macrophage polarization has been reported to induce podocyte injury, which is a typical characteristic of diabetic nephropathy (DN). Trichosanthes kirilowii is an herb showing renal protective effect as well as immune-regulating effect. Therefore, it was hypothesized that the renal
Trichosanthin induces atresia of ovarian follicles and inhibits steroidogenesis in gonadotropin-primed immature mice.
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1. Immature mice were induced to ovulate by injections of pregnant mare serum gonadotropin (PMSG) and human chorionic gonadotropin spaced 48 hr apart. 2. Trichosanthin (TCS), a protein purified from tubers of Trichosanthes kirilowii (Family Cucurbitaceae), was administered respectively 24 hr before,
Effects of SKI 306X, a new herbal agent, on proteoglycan degradation in cartilage explant culture and collagenase-induced rabbit osteoarthritis model.
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OBJECTIVE
Protective effects of SKI 306X, a natural herbal product extracted from three herbs Clematis mandshurica, Trichosanthes kirilowii, and Prunella vulgaris, on articular cartilage was examined and compared with other osteoarthritis (OA) drugs using in vitro and in vivo models.
METHODS
In
Hepatoprotective effect of Trichosanthes cucumerina Var cucumerina L. on carbon tetrachloride induced liver damage in rats.
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BACKGROUND
Different parts of the plant Trichosanthes cucumerina Var cucumerina L. (cucurbitaceae) are used to treat liver disorders, traditionally. It is one among the constituents in various Ayurvedic formulations used for the treatment of liver disorders and other diseases.
OBJECTIVE
The aim of
Frequent loss of lineages and deficient duplications accounted for low copy number of disease resistance genes in Cucurbitaceae.
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BACKGROUND
The sequenced genomes of cucumber, melon and watermelon have relatively few R-genes, with 70, 75 and 55 copies only, respectively. The mechanism for low copy number of R-genes in Cucurbitaceae genomes remains unknown.
RESULTS
Manual annotation of R-genes in the sequenced genomes of
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