trichuriasis/phosphatase

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[Microparasitocenosis of the intestines and the activity of intestinal enzymes in patients with trichocephaliasis during treatment].

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Results of the studies of large intestine microflora, enterokinase and alkaline phosphatase activity in the feces of 298 children and adults suffering from trichocephaliasis are presented. Intestinal dysbacteriosis was observed in 51.7% cases, increased enterokinase activity, in 57.6% cases and

Exploration of novel in vitro assays to study drugs against Trichuris spp.

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Though trichuriasis is a significant public health problem, few effective drugs are available underscoring the need for new drug therapies. For the evaluation of trichuricidal activity of test compounds in vitro an accurate, reliable, sensitive, fast and cheap drug sensitivity assay is essential.

Myeloid cell-specific expression of Ship1 regulates IL-12 production and immunity to helminth infection.

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Helminth infection leads to the local proliferation and accumulation of macrophages in tissues. However, the function of macrophages during helminth infection remains unclear. SH2-containing inositol 5'-phosphatase 1 (Ship1, Inpp5d) is a lipid phosphatase that has been shown to play a critical role

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