uterine cervicitis/hypoxia

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Hypoxia promotes the proliferation of cervical carcinoma cells through stimulating the secretion of IL-8.

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To explore whether hypoxia and interleukin 8 (IL-8) regulate the viability and apoptosis of cervical carcinomas cells and the possible mechanism. We evaluated the expression of hypoxia inducible factor-1α (HIF-1α), IL-8 and its receptors (CXCR1 and CXCR2) in cervical cancer and cervicitis tissues by

Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix.

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BACKGROUND Tumour microenvironment is a fundamental aspect of tumour behaviour, modulating important events as cancer cell migration and invasion, as well as angiogenesis and metastisation. Among other microenvironment features, hypoxia and acidity play important roles in this modulation. As the

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