vasoactive intestinal peptide/neoplasms

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Study of Intranasal Octreotide (DP1038) in Healthy Adult Volunteers

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Octreotide is a synthetic octapeptide analog of naturally occurring somatostatin, with similar pharmacological effects but a longer duration of action. It inhibits the pathological secretion of GH from pituitary adenomas, and of serotonin and other hormones by tumors of the gastroenteropancreatic

Plastic Bronchitis and Protein Losing Enteropathy in Children With Single Ventricle Physiology

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Protein losing enteropathy (PLE) has emerged as an increasingly common complication of single ventricle palliation in children born with cyanotic congenital heart disease. This entity becomes manifest months or years after the modified Fontan operation and is thought to affect 5-15% of all patients

Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

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PRIMARY OBJECTIVES: I. Determine objective response rate in patients with locally advanced or metastatic neuroendocrine tumors treated with FR901288 (romidepsin). SECONDARY OBJECTIVES: I. Determine the toxicity of this drug in these patients. II. To measure serum tumor markers (pancreastatin,

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