RELATED APPLICATIONS
This application is a U.S. National Phase of International Application No. PCT/CN2006/002327, filed Sep. 8, 2006, designating the U.S. and published not in English as WO 2007/028341 on Mar. 15, 2007, which claims the benefit of Chinese application No. 200510098381.2, filed Sep.
BACKGROUND OF THE INVENTION
Several naturally-occurring alkaloids obtainable from Vinca rosea have been found active in the treatment of experimental malignancies in animals. Among these are leurosine (U.S. Pat. No. 3,370,057), vincaleukoblastine (vinblastine) to be referred to hereinafter as VLB
BACKGROUND OF THE INVENTION
Several naturally-occurring alkaloids obtainable from Vinca rosea have been found active in the treatment of experimental malignancies in animals. Among these are leurosine (U.S. Pat. No. 3,370,057), vincaleukoblastine (vinblastine) to be referred to hereinafter as VLB
BACKGROUND OF THE INVENTION
Several naturally-occurring alkaloids obtainable from Vinca rosea have been found active in the treatment of experimental malignancies in animals. Among these are leurosine (U.S. Pat. No. 3,370,057), vincaleukoblastine (vinblastine) to be referred to hereinafter as VLB
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the use of vinca alkaloids in combatting tumors.
2. Discussion of the Background
The dimeric alkaloids, vincristine and vinblastine, containing indol-indoline moieties from Catharanthus species are widely used as
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