vitamin a deficiency/nicotine

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A pilot beta-carotene intervention trial with Inuits using smokeless tobacco.

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The frequency of exfoliated cells with micronuclei (MNC) was used to estimate the genotoxic effect of smokeless tobacco (snuff) on the oral mucosa and to follow the response to the administration of beta-carotene (180 mg/week, given twice weekly in 6 capsules of 30 mg each). The pilot trial was

Vitamin A deficiency: effect on retinal structure of the moth Manduca sexta.

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Sphingid moths (Manduca sexta) were reared for several generations on an artificial diet deficient in vitamin A and its precursors. Retinal tissue from depleted moths was removed for histological examination. There was extensive histolysis in the retinal epithelium and underlying nervous and

Specific Upregulation of a Cotton Phytoene Synthase Gene Produces Golden Cottonseeds with Enhanced Provitamin A.

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Provitamin A (PVA) bio-fortification of crops offers a sustainable strategy to prevent the prevalence of vitamin A deficiency (VAD), one of the world's major public health problems. The present work aimed to enhance PVA accumulation in cottonseed, the main by-product in the production of cotton

Retinoic acid receptor and retinoid X receptor alterations in lung cancer precursor lesions.

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Smoking prevention will decrease lung cancer incidence in time. However, early detection would improve lung cancer prognosis in subjects at risk provided that specific markers could be identified. We previously reported that retinoic acid receptor (RAR) and retinoid X receptor (RXR) expression was

Is it time for South Africa to end the routine high-dose vitamin A supplementation programme?

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In accordance with World Health Organization guidelines, South Africa (SA) introduced routine periodic high-dose vitamin A supplementation (VAS) in 2002. These guidelines were developed after research in the 1980s and 1990s showed the efficacy of VAS in reducing childhood mortality. However, two

Possible pathomechanisms of sudden infant death syndrome: key role of chronic hypoxia, infection/inflammation states, cytokine irregularities, and metabolic trauma in genetically predisposed infants.

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Chronic hypoxia, viral infections/bacterial toxins, inflammation states, biochemical disorders, and genetic abnormalities are the most likely trigger of sudden infant death syndrome (SIDS). Autopsy studies have shown increased pulmonary density of macrophages and markedly more eosinophils in the

Social evils, poverty & health.

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There is a close association between social circumstances and health. In India, there is a significant burden of both communicable and non communicable diseases. Risk factors responsible for these conditions are underweight, unsafe sex, unsafe water, poor sanitation and hygiene, indoor smoke

Risk factors associated with denture stomatitis in the United States.

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BACKGROUND This study reports denture stomatitis (DS) prevalence from a large USA probability sample from the National Health and Nutrition Examination Survey, 1988-1994 (NHANES III). METHODS Oral examinations were performed on 3450 individuals 18-90+ years of age (mean: 59.2; SD: 0.50 years), 57.7%

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