OBJECTIVE
To identify factors (including exposure to specific antiretroviral drugs) associated with severe vitamin D deficiency (VDD) in HIV-infected individuals and to explore the effects of severe VDD and antiretroviral drug exposure on serum alkaline phosphatase (ALP) as surrogate marker of bone
Elevated serum alkaline phosphatase (ALP) is a screening marker for the diagnosis of vitamin D deficiency, which may fail to be diagnosed if serum ALP is not elevated. Here, we describe a case of vitamin D deficiency without elevation of serum ALP. A 1-year-old Japanese girl was referred to our
Vitamin D deficiency may depress bone formation but its effect on bone resorption is not well defined. As an index of bone resorption, the activity of acid phosphatase, a lysosomal enzyme found in osteoclasts, was quantitated in situ from a bone tissue smear preparation. Activity of the enzyme,
Vitamin D deficiency in adults causes osteomalacia where there is a defect in bone mineralization resulting in an excess of unmineralised osteoid in the bone matrix. The aim of this study was to evaluate the markers of bone formation: total (TALP), bone-specific alkaline phosphatase (BSALP) and
OBJECTIVE
To determine whether serum vitamin D levels are correlated with serum levels of alkaline phosphatase or not.
METHODS
Cross-sectional, observational study.
METHODS
Multi-centre study, conducted at Liaquat National Hospital and Medical College, National Medical Centre and Medicare Hospital,
BACKGROUND
The aim of this study was to estimate the prevalence of vitamin D deficiency among healthy infants and toddlers, as well as its associated factors, in Irbid, Jordan.
METHODS
A total of 275 subjects (136 infants and 139 toddlers) aged 6-36 months participated in this study. Information
The aim of this study was to evaluate the prevalence of vitamin D deficiency in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with various demographic and renal osteodystrophy markers.
METHODS
This cross-sectional, multicenter study was carried out in
This report describes the case of a 60-year-old woman with severe metabolic bone disease and fractures due to vitamin D deficiency and hyperparathyroidism. 25OHDH3 and 1,25(OH)2D3 serum levels were undetectable and increased immediately following 25OHD3 oral administration. Serum 1,25(OH)2D3
BACKGROUND
Vitamin D deficiency is a putative, pathogenic cofactor in the increase in osteopenia and osteoporosis seen in patients with Crohn's disease.
OBJECTIVE
To determine the frequency of low serum 25-hydroxy-vitamin D3 (25-OHD) levels and the associated alterations in bone mineral density in a
OBJECTIVE
To assess the vitamin D status of 9-12-year-old primary-school children in Tehran during autumn and winter 2007-2008.
METHODS
A descriptive cross-sectional study.
METHODS
Primary schools of Tehran city, Iran.
METHODS
A total of 1111 children aged 9-12 years (573 boys and 538 girls) from
OBJECTIVE
Was to investigate the effect of treatment with an IM injection, a mega dose of vitamin D3 (10,000 IU/kg) on the clinical, biochemical and radiological parameters of 40 rachitic children with vitamin D deficiency (VDD) over a period of 3 months.
METHODS
In this prospective study we
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