vitreous detachment/hypoxia

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Management of retinal vein occlusion.

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Recent research into the relationship between retinal venous occlusion and general vascular disorders has shown that retinal venous occlusion seems to be related only to systemic hypertension. The role of systemic hemorrheologic parameters in the pathophysiology of venous occlusion is a

[The central vitreo-retinal fibroplastic (edematous-fibroplastic) syndrome (author's transl)].

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This term comprises a series of symptoms with a common pathogenesis. The disease begins with disseminated foci of paravascular fibroplasia which are ophthalmoscopically visible as "stationary reflexes" (Vodovozev 1963). These foci result in the formation of vitreo-retinal adhesions. A posterior

Enzyme-induced vitreolysis can alleviate the progression of diabetic retinopathy through the HIF-1α pathway.

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OBJECTIVE We studied the mechanism by which complete posterior vitreous detachment by enzyme-induced vitreolysis alleviates the progression of diabetic retinopathy. METHODS We enrolled 50 diabetic rats and 20 normal control rats in this study. The right eyes of these diabetic rats were treated with

[Noninvasive analysis of retinal microstructure and function: challenges and a promising future].

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Challenges in the evaluation of the retinal microstructure. To facilitate evaluation of the retinal microstructure we participated in the development of a scanning laser ophthalmoscope (SLO) for 32 years. The 'retro-mode' is the latest developed lateral aperture SLO made in Japan. This instrument

Objective of pharmacologic vitreolysis.

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The goal of pharmacologic vitreolysis is to cleave the vitreoretinal junction, thereby inducing posterior vitreous detachment (PVD), and to liquefy the vitreous gel. There are several reasons to pursue a pharmacologic approach: (1) Mechanical vitrectomy is incomplete. Both at the posterior pole and

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