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waltheria indica/alkaloid

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ArticlesClinical trialsPatents
14 results

Evaluation of antidesmone alkaloid as a photosynthesis inhibitor.

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Antidesmone, isolated from Waltheria brachypetala Turcz., owns special structural features as two α,β-unsaturated carbonyl groups and a side alkyl chain that can compete with the quinones involved in the pool of plastoquinones at photosystem II (PSII). In this work, we showed that the alkaloid is an

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica.

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Chemical investigation of the dichloromethane root extract of Waltheria indica led to the isolation and characterization of 10 quinoline alkaloids, namely, 8-deoxoantidesmone (1), waltheriones E-L (2-9), and antidesmone (10). Among these, compounds 2-9 have not yet been described in the literature.

Control of root-knot nematodes using Waltheria indica producing 4-quinolone alkaloids.

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Waltheria indica exhibited strong nematocidal activity against Meloidogyne incognita, a causal agent of root-knot nematode disease. This study aimed to characterize the nematocidal metabolites and to evaluate the efficacy of the formulated extract of W. indica in the biological control

Acetylcholinesterase activity of alkaloids from the leaves of Waltheria brachypetala.

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Chemical investigation of the leaves of Waltheria brachypetala Turks (Sterculiaceae) resulted in the isolation of quinolinone alkaloids, waltherione-A, waltherione-B (N-methylwaltherione-A), 8-methoxyflindersine, and the cyclic peptide alkaloid waltherine. The inhibition of activity of

Antifungal Quinoline Alkaloids from Waltheria indica.

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Chemical investigation of a dichloromethane extract of the aerial parts of Waltheria indica led to the isolation and characterization of five polyhydroxymethoxyflavonoids, namely, oxyanin A (1), vitexicarpin (3), chrysosplenol E (4), flindulatin (5), 5-hydroxy-3,7,4'-trimethoxyflavone (6), and six

Quinolone alkaloids from Waltheria douradinha.

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A phytochemical investigation of the stems of Waltheria douradinha resulted in isolation of two 4-quinolone alkaloids, waltherione B and vanessine, along with three known alkaloids, waltherione A, antidesmone and O-methyltembamide. Their structures were elucidated on the basis of their 2D NMR

An unusual quinolinone alkaloid from Waltheria douradinha.

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The chemical investigation of the methanolic extract of the root bark of Waltheria douradinha (Sterculiaceae) afforded an unusual quinolinone alkaloid named waltherione-A (1). Its structure was determined mainly by NMR spectroscopic methods. The antibacterial activity of waltherione-A (1) and the

[Reptide alkaloids. V. Structures of adouetines X,Y,Y1, and Z, the alkaloids of Waltheria americana L. (Sterculiaceae)].

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[The adouetins X, Y and Z, alkaloids of Waltheria americanan L. (Sterculia)].

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[Pharmacodynamic study of adouetin Z, alkaloid of Waltheria americana L. (Sterculia)].

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The Synthesis of Waltherione F and Analogues with Modifications at the 2- and 3-Positions as Potential Antitrypanosomal Agents.

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Chagas disease also know as American Trypanosomiasis (AT) is a tropical parasitic disease endemic in South America, is caused by Trypanosoma cruzi which is transmitted by the blood-sucking insect vectors called triatomine bugs. Quinoline alkaloids from the root extract of Waltheria indica are known

Botany, traditional uses, phytochemistry and pharmacology of Waltheria indica L. (syn. Waltheria americana): a review.

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BACKGROUND Waltheria indica L. (syn. Waltheria americana) is commonly used in traditional medicine in Africa, South America and Hawaii, mainly against pain, inflammation, conditions of inflammation, diarrhea, dysentery, conjunctivitis, wounds, abscess, epilepsy, convulsions, anemia, erectile

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

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Six extracts from the roots and the aerial parts of Waltheria indica L. (Malvaceae) were screened for their in vitro antitrypanosomal activity towards Trypanosoma brucei brucei STIB 427 strain, T. brucei rhodesiense STIB 900 and Trypanosoma cruzi Tulahuen C4. The dichloromethane extract from the

Prediction of the Passive Intestinal Absorption of Medicinal Plant Extract Constituents with the Parallel Artificial Membrane Permeability Assay (PAMPA).

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At the early drug discovery stage, the high-throughput parallel artificial membrane permeability assay is one of the most frequently used in vitro models to predict transcellular passive absorption. While thousands of new chemical entities have been screened with the parallel artificial membrane
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