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withasteroid/physalis angulata

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ArticlesClinical trialsPatents
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Physanolide A, a novel skeleton steroid, and other cytotoxic principles from Physalis angulata.

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[reaction: see text] A novel withasteroid, physanolide A (1), with an unprecedented skeleton containing a seven-membered ring, and two new physalins, physalins U (2) and V (3), were isolated from Physalis angulata. The structures were elucidated from spectroscopic analysis, and plausible

Trypanocidal activity of a new pterocarpan and other secondary metabolites of plants from Northeastern Brazil flora.

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Two hundred fifteen compounds isolated from plants of Northeastern Brazil flora have been assayed against epimastigote forms of Trypanosoma cruzi, using the tetrazolium salt MTT as an alternative method. Eight compounds belonging to four different species: Harpalyce brasiliana (Fabaceae), Acnistus
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