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xanthine/inflammation
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Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
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FIELD OF THE INVENTION
The present invention relates to novel pharmaceutical compositions of matter comprising xanthines and one or more analgesic agents, or xanthines and an anti-inflammatory agent, and to methods of using said compositions to hasten the onset of an analgesic or anti-inflammatory
Enatiomerically pure hydroxylated xanthine compounds to treat inflammatory diseases
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TECHNICAL FIELD OF THE INVENTION
The invention relates to a discovery that an isomer of a hydroxy-substituted xanthine compound is an effective agent to modulate cellular responses to stimuli mediated through a stereo-specific cellular second messenger pathway. More specifically, the inventive
Use of antibodies to TNF or fragments derived thereof and xanthine derivatives for combination therapy and compositions therefor
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FIELD OF THE INVENTION
The present invention relates to a pharmaceutical product for the treatment of conditions associated with elevated levels of tumour necrosis factor-.alpha. (herein referred to as TNF) and to the manufacture of such a product. The pharmaceutical product may, for example, be
Method of using pentoxifylline for treating inflammation
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It is known that 1-(5-oxohexyl)-3,7-dimethylxanthine (pentoxifylline) is used as a pharmaceutical agent for the improvement of the flow properties of blood. The supposed cause of this is (Deutsche mediz, Wochenschrift 107 (1982), 1674) that the viscous stress of the blood decreases because the
Novel xanthine derivatives
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The present invention relates to novel xanthine derivatives having pharmaceutical utility, processes for their production, pharmaceutical compositions comprising them and their use as pharmaceuticals.
More particularly the present invention provides: a compound of formula I ##STR2## wherein R.sub.1
Phenyl xanthine derivatives
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FIELD OF THE INVENTION
The present invention relates to glycol derivatives of xanthines, processes for their preparation, pharmaceutical formulations comprising them, and their use in medicine, particularly in the treatment and prophylaxis of inflammatory conditions, immune disorders, septic shock,
Pyrazole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/JP2014/059912 filed Mar. 28, 2014, claiming priority based on Japanese Patent Application No. 2013-072788 filed Mar. 29, 2013, the contents of all of which are incorporated herein by
2-aryl selenazole compound and pharmaceutical composition thereof
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This application is the U.S. national phase of International Application No. PCT/CN2013/087736 Filed on 24 Nov. 2013 which designated the U.S. and claims priority to Chinese Application Nos. CN201210504310.8 filed on 30 Nov. 2012, the entire contents of each of which are hereby incorporated by
Non-thiopurine methyltransferase related effects in 6-mercaptopurine therapy
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FIELD OF THE INVENTION
The present invention provides a method for optimizing therapeutic efficacy and predicting tolerance of 6-mercaptopurine (6-MP) drug treatment, especially in an immune-mediated gastrointestinal disorder.
BACKGROUND OF THE INVENTION
Mercaptopurine (6-MP or 6-thiopurine) and
Non-thiopurine methyltransferase related effects in 6-mercaptopurine therapy
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FIELD OF THE INVENTION
The present invention provides a method for optimizing therapeutic efficacy and predicting tolerance of 6-mercaptopurine (6-MP) drug treatment, especially in an immune-mediated gastrointestinal disorder.
BACKGROUND OF THE INVENTION
Mercaptopurine (6-MP or 6-thiopurine) and
Method for the preventing and/or treating IL-1 beta lung pathology in mammals by administering a uric acid reducing compound
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This application is a U.S. National Stage application of PCT/EP2009/062159, filed Sept. 18, 2009, which claims priority to European Patent Application No. 083055657, filed Sept. 18, 2008, each and all of which are incorporated herein by reference in their entirety.
The present invention is directed
Cosmetic preparation with a peptide addition
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention concerns a new cosmetic preparation containing peptide derivatives derived from .alpha.-MSH (melanocyte stimulating hormone) and other active ingredients.
2. The Prior Art
.alpha.-MSH has already been investigated by a number of
2-phenylpyridine derivative
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This is a national stage application under 35 U.S.C. .sctn.371 of PCT/JP2005/015549 filed on Aug. 26, 2005, which claims priority from Japanese patent application P.2004-249275 filed on Aug. 27, 2004 and from Japanese patent application P.2005-078222 filed on Mar. 17, 2005, all of which are
2-phenylthiophene derivative
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TECHNICAL FIELD
The present invention relates to a 2-phenylthiophene derivative useful as a medicament, particularly a therapeutic or preventive agent for diseases in which xantine oxidase participates, such as hyperuricemia, gout, inflammatory bowel diseases, diabetic kidney diseases, and diabetic
Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease
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TECHNICAL FIELD
This invention describes a nutritional composition and method of use for prevention of Parkinson's disease, therefore relating to the fields of nutrition, pharmacology, neurology, pathophysiology, medicine and movement disorders.
DESCRIPTION OF THE RELATED ART
Parkinson's disease
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