xylenol/necrosis

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[Experimental study of topical uses of para-chloro-methyl-xylenol in burns: therapeutic effect against Staphylococcus aureus].

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The therapeutic effect of para-chloro-methyl-xylenol (PCMX), a disinfectant of phenol compound, against Staphylococcus aureus infection in burns is evaluated in the present article. The MIC of PCMX is 50 micrograms/ml. Experimental study was done on deep burn wounds of white rabbit. Bacterial stock

The effects of drilling on revascularization and new bone formation in canine femoral heads with avascular necrosis: an initial study.

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In this study, the effects of drilling on revascularization and new bone formation were evaluated in nine dogs with surgically induced avascular necrosis (AVN) of the femoral head. Six animals had holes drilled from the greater trochanter into the femoral head at the time of vascular interruption.

Distraction osteogenesis for lengthening of the hard palate: Part II. Histological study of the hard and soft palate after distraction.

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To correct velopharyngeal incompetence, a new treatment concept was proposed in Distraction Osteogenesis for Lengthening of the Hard Palate: Part I (using lengthening of the hard and soft palate by distraction osteogenesis). Cephalometry and computed tomography showed successful elongation of the

Cytokine release and cytotoxicity in human keratinocytes and fibroblasts induced by phenols and sodium dodecyl sulfate.

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Phenolic compounds used in pharmaceutical and industrial products can cause irritant contact dermatitis. We studied the effects of resorcinol, phenol, 3,5-xylenol, chloroxylenol, and 4-hexyl-resorcinol on normal human epidermal keratinocytes and dermal fibroblasts for cytotoxicity and cytokine

Role of p21 and oxidative stress on renal tubular resistance after acute ischaemic injury.

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BACKGROUND Subsequent ischaemic episodes may induce renal resistance. P21 is a cell cycle inhibitor that may be induced by oxygen-free radicals and may have a protective effect in ischaemic acute kidney injury (AKI). This study aimed at evaluating the role of oxidative stress and p21 on tubular

Oxidative-stress biomarkers in patients with pulmonary hypertension.

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This controlled, prospective, nonrandomized clinical investigation has as its chief strength the fact that it was done in humans with active disease and apparently on fairly modest therapeutic regimens. The aim was to present the results of oxidative-stress biomarkers in humans suffering from

Assessment of cell death studies by monitoring hydrogen peroxide in cell culture.

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Hydrogen peroxide (H2O2) has been widely used to study the oxidative stress response. However, H2O2 is unstable and easily decomposes into H2O and O2. Consequently, a wide range of exposure times and treatment concentrations has been described in the literature. In the present study, we established

Role of heme oxygenase-1 in polymyxin B-induced nephrotoxicity in rats.

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Polymyxin B (PMB) is a cationic polypeptide antibiotic with activity against multidrug-resistant Gram-negative bacteria. PMB-induced nephrotoxicity consists of direct toxicity to the renal tubules and the release of reactive oxygen species (ROS) with oxidative damage. This study evaluated the

Effects of taurine supplementation following eccentric exercise in young adults.

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The purpose of the present study was to investigate the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation response after eccentric exercise (EE) in males. Twenty-one participants (mean age, 21 ± 6 years; weight, 78.2 ± 5 kg; height, 176 ± 7 cm) were

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