Journal of Pharmaceutical Sciences 1984-Apr
Serotonergic receptor antagonist from Nandina domestica Thunberg.
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Abstracto
A crude methanolic extract of the fruit of Nandina domestica Thunberg strongly inhibits serotonin-induced contractions of the rabbit aorta. The extract of the fruit has been fractionated to afford nantenine (O- methyldomesticine ) as the active agent.