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antidiabetic/obesidad

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Epicardial Fat Thickness and Inflammation in People With Metabolic Syndrome and Obesity

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Epicardial adipose tissue (EAT) is a kind of VAT, between the surface of the myocardium and the epicardium. It can easily be measured by standard two-dimensional (2D) echocardiography. EAT serves as an endocrin organ that secretes hormones, inflammatory citokins and chemokines. Previous data

Efficacy of Phosphatidylcholine in NAFLD

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As a result of increasing rates of obesity Non Alcoholic Fatty Liver (NAFLD) is the most common liver disorder affecting 17-46% of adults and parallels the prevalence of Metabolic Syndrome (MetS) and its components which also increases the risk of more advanced disease both in adults and in

GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response

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Incretins, the analogs of glucagon-like peptide-1 (GLP-1), improve glucose control in type 2 diabetes mellitus and counteract obesity through mechanisms that are not completely understood. The investigators' preliminary data show that, in prediabetic human subjects and mice, GLP-1 analog therapy

Stevia Rebaudiana Bertoni on Levels of GCF Glucose and Bio-markers in Diabetics.

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Stevia is considered as a novel molecule, because it is 100% natural and non caloric sweetener, with more sweetness than sucrose, without any adverse effects. It also demonstrates multiple benefits like anti-plaque effect, anti-diabetic effect, anti-periodontophatics properties, anti-hypertensive

Prospective Interventional Study on Reversibility of Type 2 Diabetes Mellitus With Hypocaloric Diet

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The objective is to study the effect of LCD in anthropometric , biochemical and NAFLD (Non Alcholic Fatty Liver Disease) parameters after 8 weeks and 24 weeks from enrollment. Purposive sampling is used to enroll participants in the study. The LCD is a combination of one meal replacer and modified

Effects of SGLT2i on the Cognitive Function in T2DM Patient (ESCDP)

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Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus

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STUDY OBJECTIVES Specific Aim 1: Determine the effect of MCS during pregnancy on birth weight in GDM. Specific Aim 2: Determine the influence of MCS on macronutrient transport and epigenetic modifications in the placenta and cord blood. HYPOTHESIS Aim 1: The investigators hypothesize that the

Smectite Gel and Probiotic for Obesity and Insulin Resistance

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In this single-center double-blind, placebo controlled, parallel group study, 55 type 2 diabetes patients from the Kyiv City Clinical Endocrinology Center were selected. They were randomly assigned to receive "Symbiter Smectite" or placebo for 8 weeks, administered as a sachet formulation in

Effectiveness of SCDM in Patients With Type 2 Diabetes

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Diabetes is a complex, chronic illness requiring continuous medical care with multifactorial risk-reduction strategies beyond glycemic control. At present, about 114 million diabetics and 11.6% incidence rate of diabetes in China have produced huge chronic disease management pressure and created

Role of the Ketogenic Diet in Women With PCOS

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Polycystic ovary syndrome (PCOS) is one of the most common endocrinal abnormalities that affect females within the reproductive age, and are found in about 4% of women. PCOS is commonly associated with symptoms of increased testosterone such as irregular or absent menstrual cycle, increased body

Clinical Study on the Improvement of Diabetic Neuropathic Pain by Liraglutide

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1. Diabetic neuropathic pain seriously affects the quality of life, clinical problems are difficult, and new treatment methods are urgently needed. Diabetic neuropathy is one of the most common complications of diabetes mellitus. The study of investigators shows that the prevalence rate of diabetic

Glycemic Index Variations In the Early Period Following Bariatric Surgery

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Type 2 diabetes mellitus (T2DM) is one of the most prevalent and deadly conditions in the 21st century. T2DM is characterized by obesity and insulin resistance that leads to chronic hyperglycemia, which even with best medical care is often uncontrolled, resulting in life-threatening micro- and

Glycemic Variability Comparing Two vs Six Meals in Type 2 Diabetes

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In general, hypocaloric plans for patients with type 2 diabetes mellitus are consumed in five or six small meals per day. Eating more often is presumed to reduce hunger and thus energy consumption. However, the effects of meal frequency on human health and longevity are unclear. Therefore, this

High-intensity Interval Training for Obese Individuals

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Significance The obesity epidemic is a worldwide public health problem. Recent data indicate that over 650 million adults around the world (~13%) are considered obese. Obesity is one of the major risk factors for type 2 diabetes mellitus (T2D) and 90% of T2D cases are attributable to excess fat

Influence of Preprandial Metformin Administration on Carbohydrate Absorption

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