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Antiproliferative effect of Toona sinensis leaf extract on non-small-cell lung cancer.

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Toona sinensis (TS), which is also known as Cedrela sinensis, belongs to Meliaceae family, the compounds identified from this TS leaves possess a wide range of biologic functions, such as hypoglycemic effects, anti-LDL glycative activity, antioxidant activities, and inhibition of sudden acute

Use of infliximab, an anti-tumor necrosis alpha antibody, for inflammatory dermatoses.

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BACKGROUND Infliximab is a monoclonal antibody against tumor necrosis factor alpha currently approved by the U.S. FDA for the treatment of Crohn's disease and rheumatoid arthritis. Recently, a controlled trial reported its effectiveness for psoriasis. OBJECTIVE The object of our study was to

What can we learn from the errors in the frozen section diagnosis of pulmonary carcinoid tumors? An evidence-based approach.

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The intraoperative diagnosis of pulmonary neuroendocrine tumors can be difficult. Frozen section diagnosis was requested on 87 neuroendocrine tumors including 58 typical carcinoids, 8 atypical carcinoids, 18 large cell neuroendocrine carcinomas, and 3 small cell carcinomas from 2405 patients that

Elevated soluble tumor necrosis factor receptor levels in seasonal allergic rhinitis patients.

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In this study, we examined the symptom scores and tumor necrosis factor-alpha (TNF-alpha), p55 soluble tumor necrosis factor receptor (sTNFR1), and p75 soluble tumor necrosis factor receptor (sTNFR2) levels in the sera and nasal epithelial lining fluids (ELF) of 20 patients with Japanese cedar

Discordance between pathologic and radiologic tumor size on breast MRI may contribute to increased re-excision rates.

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Preoperative breast MRI does not decrease re-excision rates in patients who undergo lumpectomy. We evaluated concordance of tumor size on MRI and pathologic size in patients who underwent re-excision of margins after lumpectomy. A retrospective review of patients at the Cedars-Sinai Breast Center

Differential gene expression between normal and tumor-derived ovarian epithelial cells.

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The majority of ovarian tumors arise from the transformation of the ovarian surface epithelial cells, a single layer of cells surrounding the ovary. To identify genes that may contribute to the malignant phenotype of ovarian cancers, cDNA representational difference analysis was used to compare

Local levels of soluble tumor necrosis factor receptors in patients with allergic rhinitis are regulated by amount of antigen.

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OBJECTIVE To examine the possible correlation between the amount of antigen and the level of soluble tumor necrosis factor receptor (sTNFR), and to assess its biologic significance in allergic reactions. METHODS Randomized control trial. METHODS Twelve volunteers with Japanese cedar pollinosis and

Post treatment surveillance of type II endometrial cancer patients.

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OBJECTIVE There are few studies analyzing surveillance for Type II endometrial cancer recurrence. Our objective was to determine the types of post treatment surveillance tests performed in our institution and the efficacy of these tests in detecting recurrence in type II endometrial cancer

What is the role of reassessment laparoscopy in the management of gynecologic cancers in 1995?

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One hundred fifty-four patients with a diagnosis of ovarian, primary peritoneal, or fallopian tube carcinoma underwent 181 reassessment procedures to detect persistent or recurrent disease between January 1, 1989 and December 31, 1994 at Cedars-Sinai Medical Center. One hundred four laparoscopic

The presence of isolated tumor cells and micrometastases in the intrathoracic lymph nodes of patients with lung cancer is not associated with decreased survival.

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The prognostic role of small intrathoracic nodal metastases in primary patients with lung cancer has been controversial, and it is unclear how their presence should be used for pathologic staging and treatment planning. The intrathoracic lymph nodes from 266 clinical stage I non-small cell carcinoma

Tumor marker trends in asymptomatic women at risk for ovarian cancer: relevance for ovarian cancer screening.

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The purpose of our study was to examine single and serial determinations of five biomarkers in asymptomatic women at risk for epithelial ovarian cancer to define median values and trends in a cancer-free cohort. Women were enrolled in the Gilda Radner Ovarian Cancer Detection program at Cedars-Sinai

SU-E-J-08: Dependence of Imaging Dose on Image Quality of Free-Breathing 3DCBCT of Moving Tumors.

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OBJECTIVE To evaluate the impact on free-breathing CBCT (FBCBCT) image quality to properly visualize the motion range of moving tumors as a function of imaging dose. METHODS A multi-purpose body phantom (QUASAR) with a cylindrical cedar wood (density = 0.330g/cc), and an embedded 3-cm diameter

Markerless motion tracking of lung tumors using dual-energy fluoroscopy.

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OBJECTIVE To evaluate the efficacy of dual-energy (DE) vs single-energy (SE) fluoroscopic imaging of lung tumors using a markerless template-based tracking algorithm. METHODS Ten representative patient breathing patterns were programmed into a Quasar™ motion phantom. The phantom was modified by

Cardiac abnormalities associated with pheochromocytoma and other adrenal tumors.

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OBJECTIVE To study the specific cardiac abnormalities associated with pheochromocytoma and to suggest a strategy for evaluating cardiac function in patients with pheochromocytoma. METHODS In this case-control study, we reviewed pathology records of patients seen at Cedars-Sinai Medical Center

Use of evidence-based guidelines reduces radioactive iodine treatment in patients with low-risk differentiated thyroid cancer.

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OBJECTIVE The goal was to determine if there was a relation between the introduction of evidence-based radioactive iodine (RAI) treatment guidelines for differentiated thyroid cancer (DTC) at Cedars-Sinai Medical Center (CSMC) and subsequent RAI use. In addition, we compared RAI treatment rates for

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