Cryptosporidium parvum (the cause of cryptosporidiosis) has become one of the most common enteropathogens causing diarrhea worldwide. Symptoms associated with cryptosporidiosis are very debilitating especially in the immunocompromised subject (e.g., AIDS patient). Clinical features include severe, chronic diarrhea, abdominal cramps, fatigue, weight loss, etc. which lead to increased health care costs and increased mortality. There is disclosed herein a method of inhibiting the severity of Cryptosporidium parvum infection by enterally administering a therapeutically effective amount of Lactobacillus reuteri.

Lactobacillus reuteri to inhibit cryptosporidiosis in mammals

Cryptosporidium parvum (the cause of cryptosporidiosis) has become one of the most common enteropathogens causing diarrhea worldwide. Symptoms associated with cryptosporidiosis are very debilitating especially in the immunocompromised subject (e.g., AIDS patient). Clinical features include severe, chronic diarrhea, abdominal cramps, fatigue, weight loss, etc. which lead to increased health care costs and increased mortality. There is described herein a method of inhibiting the severity of Cryptosporidium parvum infection by enterally administering a therapeutically effective amount of Lactobacillus acidophilus.

Abbott Laboratories

Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals

This invention relates to the amelioration of cryptosporidiosis symptoms, such as diarrhea, caused by the parasite crypotosporidium in susceptible host animals using effective amounts of decoquinate.

The Ohio State University

Rhone-Poulenc Inc.

Cryptosporidiosis amelioration

A method of reducing symptoms associated with cryptosporidia infection in mammals including humans in which L. reuteri cells are administered to the mammal in an amount sufficient to reduce diarrhea in the animal to a normal level. Daily administration as soon as cryptosporidia infection symptom are observed optimizes results. The L. reuteri cells may also be administered prophylactically to a mammal before exposure to cryptosporidia. The cells may be administered suspended in a liquid or in dry form.

cryptosporidiosis/diarrea

Lactobacillus reuteri to inhibit cryptosporidiosis in mammals

Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals

Cryptosporidiosis amelioration

Treatment of cryptosporidium infections

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