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cytomegalovirus retinitis/cefalea

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Cyclohexylamine derivatives as subtype selective N-Methyl-D-Aspartate antagonists

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FIELD OF THE INVENTION The invention provides cyclohexylamine derivatives as N-Methyl-D-Aspartate (NMDA) antagonists, pharmacological compositions comprising the derivatives, and methods of treating diseases and disorders responsive to antagonism of NMDA receptors using the derivatives. BACKGROUND

4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs, as well as novel intermediates of the 4-substituted analogs. The analogs are selectively active as antagonists of

4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs, as well as novel intermediates of the 4-substituted analogs. The analogs are selectively active as antagonists of

2-substituted piperidine analogs and their use as subtype-selective NMDA receptor antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as

2-substituted piperidine analogs and their use as subtype-selective NMDA receptor antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as

4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also

Piperidine derivatives as subtype selective N-Methyl-D-Aspartate antagonists

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FIELD OF INVENTION The invention relates to piperidine derivatives as N-Methyl-D-Aspartate (NMDA) antagonists useful in the treatment of diseases and disorders responsive to antagonism of NMDA receptors. BACKGROUND OF THE INVENTION Many of the physiological and pathophysiological effects of the

Subtype-selective NMDA receptor ligands and the use thereof

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as

Subtype-selective NMDA receptor ligands and the use thereof

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as

Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases

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FIELD OF THE INVENTION This invention is related to branched chain amino acid-dependent amino transferase (BCAT) inhibitors. The invention is also directed to the use of BCAT inhibitors as neuro-protective agents for treating conditions such as stroke, cerebral ischemia, central nervous system

Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases

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FIELD OF THE INVENTION This invention is related to branched chain amino acid-dependent amino transferase (BCAT) inhibitors. The invention is also directed to the use of BCAT inhibitors as neuro-protective agents for treating conditions such as stroke, cerebral ischemia, central nervous system
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