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Allergic contact dermatitis from gardenia fruit.
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A 41-year-old man, with severe itchy dermatitis on the left leg, had treated a bruise on the left knee with a topical folk remedy called Sokujikoh, which contains about 16% powdered gardenia fruit. After 4 days, an exacerbation of symptoms appeared, with edema, erythema, and vesicles on the treated
Preventive Effects of Gardenia jasminoides on Cerulein-Induced Chronic Pancreatitis
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Our previous report revealed that Gardenia jasminoides (GJ) has protective effects against acute pancreatitis. So, we examined whether aqueous extract of GJ has anti-inflammation and antifibrotic effects even against cerulein-induced chronic pancreatitis (CP). CP was induced in mice by an
Gardenia jasminoides protects against cerulein-induced acute pancreatitis.
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OBJECTIVE
To investigate the effect of Gardenia jasminoides (GJ) on cerulein-induced acute pancreatitis (AP) in mice.
METHODS
C57BL/6 mice weighing 18-20 g were divided into three groups. (1) Normal saline-treated group, (2) treatment with GJ at a dose of 0.1 g/kg, (3) treatment with GJ at a dose of
The Gardenia jasminoides extract and its constituent, geniposide, elicit anti-allergic effects on atopic dermatitis by inhibiting histamine in vitro and in vivo.
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BACKGROUND
Gardenia jasminoides Ellis has been used in traditional medicine for treatment of inflammation, edema, and dermaitis. The aim of this study was to investigate the mechanism by which Gardenia jasminoides extract (GJE) elicits anti-allergic effects in mast cells and in mice with atopic
Antiinflammatory effects of genipin, an active principle of gardenia.
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Genipin, the aglycone of geniposide, is metabolically produced from the geniposide in body tissues. The purpose of this study is to clarify some pharmacological actions of genipin. Genipin showed concentration-dependent inhibition on lipid peroxidation induced by Fe++/ascorbate in rat brain
Anti-inflammatory evaluation of gardenia extract, geniposide and genipin.
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Gardenia fruit has been traditionally used as a folk medicine for centuries in Asian countries. Extraction with ethanol was used to obtain an extract (GFE) that contains two known constituents, geniposide and genipin, which were subsequently evaluated for anti-inflammatory activity. GFE, genipin,
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