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6 resultados
Geraniol inhibits murine skin tumorigenesis by modulating COX-2 expression, Ras-ERK1/2 signaling pathway and apoptosis.
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Geraniol (GOH), a naturally occurring monoterpene, has been shown to have antiproliferative, cell cycle arrest and apoptosis-inducing effects, and represents a promising cancer chemopreventive agent. In the present study, we investigated the chemopreventive potential of GOH (50 and 100 mg kg(-1)
Geraniol ameliorates TNBS-induced colitis: Involvement of Wnt/β-catenin, p38MAPK, NFκB, and PPARγ signaling pathways.
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OBJECTIVE
Geraniol, a natural component of plant essential oils, exhibits potent chemopreventive effects in the colon; however, its possible role/mechanisms in experimental colitis have not been elucidated, which is the aim of this study.
METHODS
To fulfill this goal, rats were treated for 11days
[Profile-effect on quality control of Houttuynia cordata injection].
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OBJECTIVE
To find corresponding relationship between the fingerprint of Houttuynia cordata injections from different factories and their effects.
METHODS
Houttuynia cordata injections from six different factories were determined by gas chromatography (GC) and gas chromatography-mass spectra (GC-MS),
Effect of terpenes on transdermal iontophoretic delivery of diclofenac potassium under constant voltage.
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OBJECTIVE
The aim of the study was to enhance the transdermal delivery of diclofenac potassium (DP) from hydrogels by constant voltage iontophoresis (CVI). The other objective was to establish the safety and efficacy of CVI in rats.
METHODS
Hydrogels of DP were developed using hydroxyethyl cellulose
Rose geranium essential oil as a source of new and safe anti-inflammatory drugs.
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Background Since the available anti-inflammatory drugs exert an extensive variety of side effects, the search for new anti-inflammatory agents has been a priority of pharmaceutical industries. Aims The aim of the present study was to assess the anti-inflammatory activities of the essential oil of
Rose geranium essential oil as a source of new and safe anti-inflammatory drugs.
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BACKGROUND
Since the available anti-inflammatory drugs exert an extensive variety of side effects, the search for new anti-inflammatory agents has been a priority of pharmaceutical industries.
OBJECTIVE
The aim of the present study was to assess the anti-inflammatory activities of the essential oil
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