Healthy

Low dose response efficacy of plant extracts

Middle dose response efficacy of plant extracts

High Dose response efficacy of plant extracts

Placebo

Health Sciences Research Centre, Life Sciences Department, University of Roehampton

The Effect of a Botanical Plant Extract on Gut Health, Immunity and Metabolic Disorders in Healthy Adults

Double Blind Randomised Placebo Controlled Investigation Into the Effect of Supplementing Plant Extracts on Gut Health, Immunity and Metabolic Disorders in Healthy Adults

DNA profiling from faeces (bacteria numbers/g faeces)

Effects on TC, LDL-C, HDL-C and TAG expressed in mmol/L

Effect of insulin levels expressed in mg/dl

Cytokines analysis on IL6,IL10, IL2 and TNFa expressed in pg/mL

Food Dietary intake analysis via DietPlan 7

DR ADELE COSTABILE

Director of the Study

University of Roehampton

Fenugreek seeds extract 500 mg capsule twice a day for 12 weeks

Placebo capsule containing Dicalcium Phosphate 500mg, BD

Diabetes

Fenugreek seeds extract

Evaluation of Fenugreek Seed Extract In Type- 2 Diabetes: An Add-On Study

Clinical Evaluation of Fenugreek Seed Extract In Patients With Type- 2 Diabetes: An Add-On Study

Reduction in fasting blood sugar levels (FBS) (mg/dL)

Reduction in post prandial blood sugar levels (mg/dL)

Chemical Resources

The patients who were positive for H.pylori infection are entered into an eradication therapy protocol which includes oral esomeprazole 40mg daily, oral clarithromycin 500mg bd and oral amoxicillin 1000mg bd for 14 days.

Response to Levodopa

Motor Outcomes

Quality of Life Outcomes

Patients who were positive for H.pylori infection received an eradication therapy consisting of oral esomeprazole 40 md daily, oral clarithromycin 500mg bd and oral amoxicillin 1000mg bd for 14 days.

Eradication therapy for H.pylori infection

Patients who are positive on urea breath test are given eradication therapy for 14 days, Eradication therapy includes esomeprazole 40mg daily, clarithromycin 500mg bd, amoxicillin 1g bd

Eradication of Helcobacter Pylori

Eradication therapy for Helicobacter pylori

UKM Medical Center

Effects of Helicobacter Pylori Infection Eradication in Patients With Parkinson's Disease

A Study on Clinical Response Following Eradication Therapy of Helicobacter Pylori Infection in Parkinson's Disease

This was measured by asking the patient to determine the time taken to experience on from the time of ingestion of levodopa and to determine the duration of time that they are ON, while receiving levodopa.
The patients are asked to keep a diary if possible. If not, the patients are asked during their visits, baseline visit, visit 1, visit 2 and visit 3

Patients are followed up every 4 weeks, for 12 weeks ( 3 visits). The levodopa onset time is calculated based on the time taken to achieve on following levodopa ingestion, while the ON-time duration is the time the patient remains on following levodopa ingestion.
Patients are asked to keep a diary, if possible.

The patients are followed every 4 weeks, for 3 visits, and their motor disability and quality of life parameters are measured at each visit, while they are ON. The improvement is compared to baseline

glucosidase/atrofia

The Effect of a Botanical Plant Extract on Gut Health, Immunity and Metabolic Disorders in Healthy Adults

Evaluation of Fenugreek Seed Extract In Type- 2 Diabetes: An Add-On Study

Effects of Helicobacter Pylori Infection Eradication in Patients With Parkinson's Disease

OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher Disease

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