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hemorrhage/diarrea

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7 resultados

Use of phospholipase inhibitors in the treatment of Clostridium difficile diarrhea

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BACKGROUND OF THE INVENTION The bacterial-mediated diarrheal diseases include cholera, typhoid fever, traveller's diarrhea, and diarrheal illness in infants. The diseases are basically of two types, invasive and non-invasive gastroenteritis. Typhoid fever is representative of the invasive type of

1,4-dithiin and 1,4-dithiepin-1,1,4,4, tetroxide derivatives useful as antagonists of the human galanin receptor

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FIELD OF THE INVENTION This invention relates to a series of 1,4-dithiin- and 1,4-dithiepin-1,1,4,4-tetroxide derivatives and their use for the treatment of central nervous system disorders and affective conditions. More particularly, the compounds of the invention are ligands for the human galanin

2'-Ethynyl nucleoside derivatives for treatment of viral infections

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FIELD OF THE INVENTION This invention is directed to novel compounds which are useful in the treatment of viral infections. The invention is also directed to pharmaceutical compositions containing the compounds, processes for their preparation and uses of the compounds in various medicinal

2'-ethynyl nucleoside derivatives for treatment of viral infections

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FIELD OF THE INVENTION This invention is directed to novel compounds which are useful in the treatment of viral infections. The invention is also directed to pharmaceutical compositions containing the compounds, processes for their preparation and uses of the compounds in various medicinal

Monospecific polyclonal antibodies to shiga-like toxins

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FIELD OF THE INVENTION The present invention relates to antibodies to Shiga-like toxins. More particularly, it relates to high titer, monospecific, purified polyclonal antibodies to Shiga-like toxins and methods of preparing and using the antibodies. The invention also relates to the pharmaceutical

Somatostatin agonists

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BACKGROUND OF THE INVENTION The present invention is directed to cyclic peptides that have somatostatin agonist activity, as defined by formula (I), shown and defined hereinbelow, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising said peptides and the use thereof

Somatostatin agonists

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BACKGROUND OF THE INVENTION The present invention is directed to cyclic peptides that have somatostatin agonist activity, as defined by formula (I), shown and defined hereinbelow, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising said peptides and the use thereof
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