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10 resultados
Iodo-hexose compounds useful to treat cancer
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BACKGROUND
Cancer treatment regimens are frequently challenged by multi-drug resistance as tumor cells adapt in response to drug treatment. Apoptosis, a type of programmed cell death, involves a series of biochemical events that lead to changes in cell morphology and death. The apoptotic process is
Synthetic glycoamines and methods for their use that affect cell adhesion, inhibit cancer cell metastasis, and induce apoptosis
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FIELD OF THE INVENTION
The present invention relates to pharmaceuticals that affect cell adhesion, inhibit cancer cell metastasis, and induce apoptosis both in vitro and in vivo.
Background of the Invention
Cell adhesion is one important property that differentiates multi-cellular organisms from
Medicament for the treatment of viral skin and tumour diseases
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The present invention relates to a pharmaceutical which comprises a compound of the formula
##STR00001##
where R.sub.1, independent of each other, is an unbranched or branched, saturated, singly or multiply unsaturated, optionally substituted C.sub.11-C.sub.21 alkyl, alkylene or alkynyl radical,
Medicament for the treatment of viral skin and tumour diseases
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The present invention relates to a pharmaceutical which comprises a compound of the formula
##STR00002## where R.sub.1, independent of each other, is an unbranched or branched, saturated, singly or multiply unsaturated, optionally substituted C.sub.11-C.sub.21 alkyl, alkylene or alkynyl radical,
Medicament for the treatment of viral skin and tumour diseases
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The present invention relates to a pharmaceutical which comprises a compound of the formula
##STR00001## where R.sub.1, independent of each other, is an unbranched or branched, saturated, singly or multiply unsaturated, optionally substituted C.sub.11-C.sub.21 alkyl, alkylene or alkynyl radical,
Glucose uptake inhibitors
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FIELD OF THE INVENTION
This invention provides compounds that modulate glucose uptake activity. Compounds of the invention are useful for treating diseases, including cancer, autoimmune diseases and inflammation, infectious diseases, and metabolic diseases.
BACKGROUND OF THE INVENTION
Glucose
Methods of treating inflammation using cell adhesion inhibitors
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TECHNICAL FIELD
The invention relates to compounds useful in the treatment of inflammation, allergic reactions, autoimmune diseases, and related conditions. More specifically, the invention concerns substituted lactose that binds to selectin receptors and to pharmaceutical compositions containing
Composition and method for inhibiting reverse transcript of a retrovirus
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to compositions and methods for inhibiting reverse transcription, and, more particularly, to such compositions and methods for creating a nucleoside analog that disrupts the hybridization step during reverse
Glycoproteins and processes for their production
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel glycoproteins obtained from an extract or a supernatant of culture medium of reticulo-endothelial cells, lymphoblasts, leukemia cells or fibroblasts of warm-blooded animals, processes for their production and
Levo-monosaccharide in a nucleoside analog for use as an anti-retroviral agent
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to compositions and methods for inhibiting reverse transcription, and, more particularly, to such compositions and methods for creating a nucleoside analog that disrupts the hybridization step during reverse
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