7 resultados
BACKGROUND OF THE INVENTION
The clinical treatment of schizophrenia has long been defined by the dopamine hypothesis of schizophrenia, which holds that schizophrenia is a result of hyperactivity of dopaminergic neurotransmission, particularly in limbic brain structures such as nucleus accumbens (the
BACKGROUND OF THE INVENTION
The clinical treatment of schizophrenia has long been defined by the dopamine hypothesis of schizophrenia, which holds that schizophrenia is a result of hyperactivity of dopaminergic neurotransmission, particularly in limbic brain structures such as nucleus accumbens (the
This invention relates to antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one, to processes for preparing them, methods of using them and to pharmaceutical compositions containing them.
The clinical treatment of schizophrenia has long been
BACKGROUND OF THE INVENTION
The application claims priority from co-pending provisional application serial No. 60/286,229, filed on Apr. 25, 2001, the entire disclosure of which is hereby incorporated by reference.
The clinical treatment of schizophrenia has long been defined by the dopamine
This invention relates to antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-2,3-diaza-cyclopenta[a]naphthalene, to processes for preparing them, methods of using them and to pharmaceutical compositions containing them.
BACKGROUND OF THE INVENTION
The clinical treatment of
TECHNICAL FIELD
The present disclosure relates to certain amides and ureas derived from aminobutyl piperazines. Compounds of the present disclosure are dopamine D3 receptor preferring antagonist or partial agonist ligands. Compounds of the present disclosure are useful as treatment agents for
TECHNICAL FIELD
The present disclosure relates to certain amides and ureas derived from aminobutyl piperazines. Compounds of the present disclosure are dopamine D3 receptor preferring antagonist or partial agonist ligands. Compounds of the present disclosure are useful as treatment agents for CNS