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hypersensitivity/edema
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Method for preventing or treating an allergic disease using extract from illicium verum
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BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to a method for preventing or treating an allergic disease using an extract from Illicium verum.
Description of the Related Art
Allergies are known as sensitive reaction which is caused by immune dysfunction innately or
Triazine derivatives to treat pain, fever, inflammation, allergies and thrombosis
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N-nicotinoylhalogenobenzoguanamines are known in the art to exhibit strong anti-inflammatory action (see Japanese patent application No. 56-87124). It has now been discovered that triazine derivatives of the formula (I): ##STR2## and pharmaceutically acceptable salts thereof wherein R.sup.1 and
1,3-diaryl cyclopentanes and derivatives thereof as PAF antagonists
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BACKGROUND OF THE INVENTION
Platelet-activating factor (PAF) has recently been identified as an acetyl glyceryl ether phosphorylcholine (AGEPC), i.e., 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (Hanahan D. J. et al., J. Biol. Chem. 255:5514, 1980). Even before its chemical
1,3-diaryl cyclopentanes and derivatives thereof as PAF antagonists
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BACKGROUND OF THE INVENTION
Platelet-activating factor (PAF) has recently been identified as an acetyl glyceryl ether phosphorylcholine (AGEPC), i.e., 1-0-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorycholine (Hanahan D. J., et al., J. Biol. Chem. 255:5514, 1980). Even before its chemical
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein
R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl,
R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Therapeutic treatment for skin disorders
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is broadly directed to a method of inhibiting or decreasing vascular permeability associated with dermal edema, e.g., induration, and especially the increased vascular permeability induced by vascular permeability factor
Pharmaceutical composition comprising glutarimide derivatives and use thereof in the treatment of eosinophilic diseases
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FIELD OF THE INVENTION
The invention relates to the use of biologically active glutarimide derivatives or pharmaceutically acceptable salts thereof as agents for the treatment of eosinophilic diseases.
BACKGROUND
Eosinophils are cells of the innate immunity. They are produced in the bone marrow and
Phospholipid analogs useful as PAF synthesis inhibitors
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BACKGROUND OF THE INVENTION
Platelet-activating factor (PAF) has been identified as an acetyl glyceryl ether phosphorylcholine (AGEPC), i.e., 1-O-hexadecyl/octadecyl-2-O-acetyl-sn-glycerol-3-phosphorylcholine [Hanahan, D. S. et al., J. Biol. Chem., 255:5514, (1980)]. Even before its chemical
Ionic aqueous polysaccharide compositions
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BACKGROUND OF THE INVENTION
Sinonasal complaints affect at least 15% of the population in the United States of America with predictable patient morbidity and financial impact. Importantly, any modality that can alleviate sinonasal complaints warrants serious attention. Among various treatments
Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
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This application is related to, not a continuing case to U.S. Pat. Nos. 6,172,060, 6,197,778, 6,177,428, 6,172,068, 6,221,881, 6,232,321, 6,197,782, 6,133,272, and 6,211,179.
FIELD OF THE INVENTION
The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and
Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
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FIELD OF THE INVENTION
The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and novel compositions comprising at least one nitrosated and/or nitrosylated phosphodiesterase inhibitor, and, optionally, at least one compound that donates, transfers or
Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
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FIELD OF THE INVENTION
The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and novel compositions comprising at least one nitrosated and/or nitrosylated phosphodiesterase inhibitor, and, optionally, at least one compound that donates, transfers or
Substituted 2,3,3a,6-tetrahydro-6-oxobenzofuran derivative useful as PAF antagonist
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BACKGROUND OF THE INVENTION
Platelet-activating factor (PAF) has recently been identified as an acetyl glyceryl ether phosphorylcholine (AGEPC), i.e., 1-O-hexadecyl/octadecyl-2-O-acetyl-sn-glycero-3-phosphorylcholine (Hanahan, D. S. et al., J. Biol. Chem., 255: 5514, 1980). It is a potent lipid
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