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hypersensitivity/protease
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Regulation of human eosinophil serine protease 1-like enzyme
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TECHNICAL FIELD OF THE INVENTION
The invention relates to the regulation of a human eosinophil serine protease 1-like enzyme.
BACKGROUND OF THE INVENTION
Serine proteases are members of a family of proteolytic enzymes characterized by the presence of a cardinal serine in the catalytic site. They
Cysteine protease derived from parasitic helminths
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FIELD OF THE INVENTION
The present invention relates to immunosuppressive drugs used for suppression of graft rejection in organ transplantation or suppression of autoimmune diseases.
BACKGROUND OF THE INVENTION
Currently, azathiopline, cyclosporin A, FK-506, and 15-deoxysperguarine are known as
Cloning and recombinant productions of Vespula venom protease and methods of use thereof
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This application is a .sctn.371 US National Entry of International Application No. PCT/EP2010/001329, filed Mar. 3, 2010, which is incorporated herein by reference and which claims the benefit of European Application No. 09003033.9, filed Mar. 3, 2009.
The present invention relates to nucleic acids
Secretory leukocyte protease inhibitor as an inhibitor of tryptase
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FIELD
This invention relates to inhibition of proteases, and more particularly, to inhibition of tryptase by secretory leukocyte protease inhibitor (SLPI).
BACKGROUND
Vasoactive intestinal peptide (VIP) is a bronchorelaxant which is absent from or present only at relatively low levels in the lungs
Guanidine derivative and medical use thereof
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TECHNICAL FIELD
This disclosure relates to a guanidine derivative and medical use thereof.
BACKGROUND
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (hereinafter, referred to as MALT1) is cysteine protease, and activates the signal transduction of nuclear factor
Low allergenic natural rubber and method of preparing low allergenic natural rubber latex
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BACKGROUND OF THE INVENTION
The present invention relates to a method of preparing a natural rubber latex and a method of preparing a deproteinized natural rubber latex, which are less likely to cause allergy, and a low allergenic natural rubber and a deproteinized natural rubber.
Natural rubbers
Composition and method for reducing snoring and respiratory problems
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BACKGROUND
In the United States, it is estimated that approximately forty percent of the population is afflicted with snoring problems of sufficient severity to disturb the sleep of the person doing the snoring, or the mate of such a person, on a regular basis. Snoring is caused, in general, by an
Amidinophenol derivatives
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FIELD OF THE INVENTION
The present invention relates to amidinophenol derivatives.
More particularly, it relates to:
(i) amidinophenol derivatives of the formula (I): ##STR2## (wherein the various symbols are the same meaning hereafter described) and acid addition salts thereof, having an inhibitory
Peptidyl heterocyclic ketones useful as tryptase inhibitors
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FIELD OF THE INVENTION
This invention relates to a series of compounds which are peptidyl heterocyclic ketone inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders, skin
Peptidyl heterocyclic ketones useful as tryptase inhibitors
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FIELD OF THE INVENTION
This invention relates to a series of compounds which are peptidyl heterocyclic ketone inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders, skin
Tryptase inhibitor proteins derived from blood-feeding anthropod ectoparasites
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The present invention relates to novel proteins that have been identified in ticks. These proteins may be used a components of vaccines, as inhibitors of mast cell tryptase (hereafter referred to as MCT), in the detection of mast cells and in the isolation and purification of MCT. The invention also
Replication-competent recombinant viral vaccines and method of producing same
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BACKGROUND
Presently, there are many types of vaccines used to immunize individuals against disease. Although those available are generally safe and, at least to some extent, effective in inducing an immune response, all have limitations. In addition, for some diseases, there is no effective
Amidinophenol derivatives
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FIELD OF THE INVENTION
The present invention relates to amidinophenol derivatives, processes for preparation thereof and pharmaceutical compositions containing these amidinophenol derivatives.
BACKGROUND OF THE INVENTION
Phospholipase A.sub.2 (PLA.sub.2) is an enzyme which acts on phospholipids
Method for producing a hypoallergenic wheat flour
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FIELD OF THE INVENTION
The present invention relates to a method for producing a hypoallergenic wheat flour and a hypoallergenic wheat flour produced by the method. More particularly, the present invention relates to a hypoallergenic wheat flour useful as a food material for cereal-allergy patients
Compositions and methods for treating mast-cell mediated conditions
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders. The invention includes compositions and methods effective for the prevention and treatment of inflammatory
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