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inflammation/nicotina
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Colonic delivery of nicotine to treat inflammatory bowel disease
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BACKGROUND OF THE INVENTION
Inflammatory bowel disorders or diseases (IBD) encompass a spectrum of overlapping clinical diseases that appear to lack a common etiology. IBD, however, are characterized by chronic inflammation at various sites in the gastrointestinal (GI) tract. Illustrative IBD are
Colonic delivery of nicotine to treat inflammatory bowel disease
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BACKGROUND OF THE INVENTION
Inflammatory bowel disorders or diseases (IBD) encompass a spectrum of overlapping clinical diseases that appear to lack a common etiology. IBD, however, are characterized by chronic inflammation at various sites in the gastrointestinal (GI) tract. Illustrative IBD are
Nicotinic receptor agonists for the treatment of inflammatory diseases
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FIELD OF THE INVENTION
The present invention relates to the treatment of inflammatory diseases, including a variety of pulmonary diseases, through the use or administration of nicotinic receptor agonists.
BACKGROUND OF THE INVENTION
Although we breathe more than one cubic meter of air every hour,
Nicotinic attenuation of CNS inflammation and autoimmunity
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BACKGROUND
All publications herein are incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference. The following description includes information that may be useful in understanding
Nicotinic attenuation of CNS inflammation and autoimmunity
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BACKGROUND
All publications herein are incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference. The following description includes information that may be useful in understanding
Nicotinic attenuation of CNS inflammation and autoimmunity
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BACKGROUND
All publications herein are incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference. The following description includes information that may be useful in understanding
Nicotinic receptor agonists for the treatment of inflammatory diseases
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FIELD OF THE INVENTION
The present invention relates to the treatment of inflammatory diseases, including a variety of pulmonary diseases, through the use or administration of nicotinic receptor agonists.
BACKGROUND OF THE INVENTION
Although we breathe more than one cubic meter of air every hour,
Nicotinic receptor agonists for the treatment of inflammatory diseases
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BACKGROUND OF THE INVENTION
a) Field of the Invention
The present invention relates to the treatment of inflammatory diseases, including a variety of pulmonary diseases, through the use or administration of nicotinic receptor agonists or analogs and derivatives thereof.
b) Description of Prior
Nicotinic receptor agonists for the treatment of inflammatory diseases
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BACKGROUND OF THE INVENTION
a) Field of the Invention
The present invention relates to the treatment of inflammatory diseases, including a variety of pulmonary diseases, through the use or administration of nicotinic receptor agonists or analogs and derivatives thereof.
b) Description of Prior
Nicotinic receptor agonists for the treatment of inflammatory diseases
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BACKGROUND OF THE INVENTION
a) Field of the Invention
The present invention relates to the treatment of inflammatory diseases, including a variety of pulmonary diseases, through the use or administration of nicotinic receptor agonists or analogs and derivatives thereof.
b) Description of Prior
Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a national phase entry under 35 U.S.C. .sctn.371 of International Application No. PCT/US2012/042254 filed Jun. 13, 2012, which claims the benefit of priority of a continuation-in-part application Ser. No. 12/009,649 filed 22 Jan.
Nicotine receptor targeted compounds and compositions
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BACKGROUND OF THE INVENTION
Acetylcholine receptors can be divided into muscarinic (mAChR) and nicotinic (nAChR) subtypes in the mammalian central nervous system (CNS). These subtypes are distinguished based on their ability to be stimulated by either the mushroom toxin muscarine or the plant
Composition and methods for treatment of neurological disorders and neurodegenerative diseases
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1. FIELD OF THE INVENTION
The present invention relates to compositions and methods for the treatment of various neurological diseases and neurodegenerative disorders, particularly those affected by an overabundance of Amyloid Precursor Protein (APP). In particular, it has been discovered that APP
Compositions and methods for treatment of neurological disorders and neurodegenerative diseases
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1. FIELD OF THE INVENTION
The present invention relates to compositions and methods for the treatment of various neurological diseases and neurodegenerative disorders, particularly those affected by an overabundance of Amyloid Precursor Protein (APP). In particular, it has been discovered that APP
Phenyl-substituted nicotinic ligands, and methods of use thereof
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BACKGROUND OF THE INVENTION
Neuronal nicotinic acetylcholine receptors (nAChRs) serve a wide range of physiological functions and have been implicated in a number of pathological processes and pharmacological effects of nicotinic drugs. Many of the important in vivo effects of nicotine in the
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