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lymphocytosis/phosphatase
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[Behavior of some leukocytic enzymes (glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase, alkaline phosphatases) in subjects of pediatric age with absolute lymphocytosis and neutrophilia].
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Fragilitas Ossium in a Family showing both Thickening and Rarefaction of Bones, Relative Lymphocytosis and raised Serum Phosphatase with Absence of Blue Sclerotics and Otosclerosis.
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Translocation of the B cell receptor to lipid rafts is inhibited in B cells from BLV-infected, persistent lymphocytosis cattle.
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Bovine leukemia virus (BLV) infection causes a significant polyclonal expansion of CD5(+), IgM+ B lymphocytes known as persistent lymphocytosis (PL) in approximately 30% of infected cattle. There is evidence that this expanded B cell population has altered signaling, and resistance to apoptosis has
The morphologic and immunophenotypic assessment of the lymphocytosis accompanying Bordetella pertussis infection.
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Bordetella pertussis (Bp) infection in infants and young children can be associated with a significant increase in small lymphocytes with convoluted and cleaved nuclei (SLCCN) in the peripheral blood (PB). Buffy coat smears were studied that were prepared from the PB of 11 children with documented
Chronic T cell lymphocytosis: a review of 21 cases.
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Twenty-one patients are described with a proliferation of morphologically mature T lymphocytes. The clinical course was chronic in most, and splenic enlargement the main clinical finding; skin involvement and lymphadenopathy were rare. The mean lymphocyte count at presentation was 8 X 10(9)/1 (range
Monoclonal lymphocytosis with villous lymphocytes: a chronic lymphoproliferative disease of CD11c+ B-cells.
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Most of the circulating lymphocytes from three asymptomatic adults (one male, two female, age range 61-67 years) with isolated persistent lymphocytosis of between 7.1 and 10 x 10(9)/l possessed characteristic villous projections of the cell membrane. Morphological, histochemical, ultrastructural,
Bovine leukemia virus transmembrane protein gp30 physically associates with the down-regulatory phosphatase SHP-1.
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In B lymphocytes, the down-regulatory phosphatase SHP-1 associates with CD22 and CD32b (also known as FcgammaRIIB) and acts as a critical negative regulator of B-cell receptor signaling. Bovine leukemia virus, a retrovirus of the HTLV/BLV group, causes persistently increased numbers of peripheral
[Polyclonal B-cell lymphocytosis with clinical and hematological features resembling hairy cell leukemia].
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A 49-year-old man was admitted to our hospital for investigation of splenomegaly and lymphocytosis. He had no significant past history and was not a smoker. Physical examination revealed massive splenomegaly and no palpable superficial lymph nodes. Hematological examination showed a hemoglobin
Chronic T cell lymphocytosis with large granular lymphocytes of helper (OKT4) phenotype.
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A 54-year-old asymptomatic male patient was followed for more than 7 y and presented a constant T cell lymphocytosis without skin involvement or bone marrow depression. No clinical or haematological aggravation was noted during this follow-up. Morphologically, the cells were large granular
CD4/Leu7 and CD8/Leu7 large granular lymphocytosis: comparative studies between NK cells and T cells.
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Lymphocytes, co-expressing CD4/Leu7 and CD8/Leu7 markers respectively, taken from two patients having large granular lymphocytosis taking an indolent clinical course have been comparatively studied for function as NK cells and T cells. Both large granular lymphocytes (LGLs) were acid phosphatase
Polyclonal B-cell lymphocytosis with features resembling hairy cell leukemia-Japanese variant.
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Polyclonal B lymphocytosis was found in four patients having clinical and hematologic features resembling those of hairy cell leukemia (HCL). All four patients were women between 37 and 67 years of age. Three patients had splenomegaly. Lymphadenopthy was absent or slight. Persistent lymphocytosis
Expression of TIA-1 and TIA-2 in T cell malignancies and T cell lymphocytosis.
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OBJECTIVE
To investigate the reactivity with TIA-1 and TIA-2, two monoclonal antibodies that recognise, respectively, granular structures in T lymphocytes and the T cell receptor chain in cells from a variety of T cell disorders.
METHODS
Cytoplasmic staining with TIA-1 and TIA-2 was carried out by
Lymphocytosis of large granular lymphocytes in three dogs.
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The clinical course and hematologic changes of three dogs with lymphocytosis of cells morphologically resembling large granular lymphocytes are presented. Hemograms from all dogs showed leukocytosis with marked lymphocytosis. Lymphocytes were characterized by abundant basophilic cytoplasm containing
The use of leukocyte acid phosphatase in the diagnosis of malignant disease. Case report and review of literature.
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Tartrate resistant acid phosphatase (TRAP) has been demonstrated during relapse in the cells in the cerebral spinal fluid (CSF) in a patient with the clinical features of acute T cell lymphocytic leukemia which suggests this isozyme may be a marker for malignant transformation of some types of
Effect of indomethacin on lysosomal acid phosphatase activity in peripheral blood lymphocytes.
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In 25 patients with discopathies and degenerative disease of the vertebral column, treated with indomethacin (Metindol, Polfa) in a dose of 100 mg per day during 10 days, the acid phosphatase (AP) activity was determined in the peripheral blood lymphocytes by means of the cytochemical method of
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