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night blindness/cefalea
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Not all cases of nyctalopia are benign: Unusual and serendipitous presentation of Arnold-Chiari Type 1 malformation at a Pediatric Tertiary Care Center.
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The Arnold-Chiari Type 1 malformation (CM1) is a rare congenital abnormality characterized by ectopia or caudal herniation of the cerebellar tonsils through the foramen magnum into the cervical spine, resulting in crowding at the craniocervical junction. It seldom presents in childhood with symptoms
Clinical findings and common symptoms in retinitis pigmentosa.
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Data analysis was performed in a prospective study of clinical symptoms and findings in 500 patients with retinitis pigmentosa. The symptoms and findings in these patients met the usual definitions of the disease. At initial examination the patients were questioned in a standardized manner; symptoms
Undetected pituitary adenoma in a patient with retinitis pigmentosa
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Background: Retinitis pigmentosa (RP) is one of the most severe hereditary retinal disorders with a worldwide prevalence reaching 1 in every 3000-5000 people and a total of almost one million affected individuals. RP is heterogeneous in
Retinitis pigmentosa in Benin, Nigeria.
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OBJECTIVE
To determine the mode of presentation and degree of visual impairment of retinitis pigmentosa in Nigerians.
METHODS
A prospective, non-comparative study.
METHODS
University of Benin Teaching Hospital, Benin City, Nigeria.
METHODS
Thirty Nigerian patients with a diagnosis of retinitis
Risk of Depressive Symptoms Associated with Morbidity in Postpartum Women in Rural Bangladesh.
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Objectives Depression following pregnancy is common, but its extent and association with maternal morbidity in the first 6 months postpartum have not been well described in low resource settings such as rural Bangladesh. Methods We used data from a population-based, community trial of approximately
Phase I trial and pharmacokinetics of fenretinide in children with neuroblastoma.
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OBJECTIVE
Fenretinide (4HPR), a synthetic retinoid, induces apoptosis in neuroblastoma cells. A Phase I study in children with neuroblastoma was designed to determine maximum tolerated dose, toxicity, and pharmacokinetics.
METHODS
Fifty-four patients received oral 4HPR, once daily, for 28 days,
Phenotypic expression of Bardet-Biedl syndrome in patients homozygous for the common M390R mutation in the BBS1 gene.
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OBJECTIVE
To characterize the phenotype of Bardet-Biedl syndrome (BBS) patients homozygous for the BBS1 M390R mutation.
METHODS
Three patients [PT1, F, 27 years old (yo) at last examination, 14-year follow-up (F/U) PT2, F, 15-yo PT3, M, 15-yo, both 1-year F/U] underwent eye exams, Goldmann visual
'Visual snow' - a disorder distinct from persistent migraine aura.
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Patients with 'visual snow' report continuous tiny dots in the entire visual field similar to the noise of an analogue television. As they frequently have migraine as a comorbidity with ophthalmological, neurological and radiological studies being normal, they are offered various diagnoses,
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