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nonivamide/eritema
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4 resultados
The effect of the base on the kinetics of action of the capsaicinoid nonivamide: evaluation with a hyperemic test.
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Because of their selective receptor-mediated action on cutaneous nociceptive C-fibers, the interest in capsaicinoids as topical analgetic drugs has been constantly growing over the past years. Knowledge of the pharmacokinetics seems particularly important for potential future clinical applications.
In vitro and in vivo evaluations of topically applied capsaicin and nonivamide from hydrogels.
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The purpose of this study was designed to investigate the in vitro and in vivo skin absorption of capsaicin and nonivamide from hydrogels. Various commercialized creams of capsaicin were also compared with hydrogels. Both skin stripping technique and Mexameter were applied to evaluate the level of
Quantification of cutaneous pharmacological reactions: comparison of laser Doppler scanning, colorimetry, planimetry and skin temperature measurement.
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OBJECTIVE
2-dimensional laser Doppler scanning distinguishes itself particularly by its good reproducibility with regard to both time and site. The aim of this study was to investigate this relatively new procedure in localised hyperaemic reactions and to compare it to already established
Assessment of pepper spray product potency in Asian and Caucasian forearm skin using transepidermal water loss, skin temperature and reflectance colorimetry.
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Historically, pepper spray product potency has been established using a taste test evaluation. A taste test is subjective and may not be appropriate for assessing pepper potency in skin. The current study evaluated chemically diverse pepper sprays in human forearm skin using three objective,
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