the study involves the intake of two capsules per day, one capsule to be taken before breakfast and one before dinner for a period of 6 weeks of a nutritional supplement
INTERVENTION CAPSULE COMPOSITION active substances for 2 capsules Bio Curcumin 400 mg Polydatin 00 mg Beta-Caryophyllene 48 mg

particpants included in the placebo group will take two capsules per day (containing no bioactive compound, only hydroxypropyl methylcellulose, gellan gum, pigment), one capsule to be taken before breakfast and one before dinner for a period of 6 weeks.

Osteoarthritis

Knee Pain Chronic

two capsules per day, one capsule to be taken before breakfast and one before dinner for a period of 6 weeks.

Experimental: Curcumin derivate

two capsules per day (containing no bioactive compound, only hydroxypropyl methylcellulose, gellan gum, pigment), one capsule to be taken before breakfast and one before dinner for a period of 6 weeks.

Placebo

Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in Osteoarthritis

Evaluation of the Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in People With Osteoarthritis

WOMAC scale is a self-administered questionnaire consisting of 24 items divided into 3 subscales:
Pain (5 items): during walking, using stairs, in bed, sitting or lying, and standing upright Stiffness (2 items): after first waking and later in the day Physical Function (17 items): using stairs, rising from sitting, standing, bending, walking, getting in / out of a car, shopping, putting on / taking off socks, rising from bed, lying in bed, getting in / out of bath, sitting, getting on / off toilet, heavy domestic duties, light domestic duties
The test questions are scored on a 0-4 scale, corresponding to: None (0), Mild (1), Moderate (2), Severe (3), and Extreme (4).
The scores for each subscale are summed up; higher scores on the WOMAC indicate worse pain, stiffness, and functional limitations

Serum CRP levels were assessed by means of a commercially available CRP enzyme immunoassay

Levels of TNF-alpha, IL-1beta, IL-6, nitrates/nitrites will be evaluated by means of ELISA-testing

Painkillers utilization will be registered on a daily basis by participants, indicating dosage and daily frequency of use.

KOS Care SRL - Istituto di Riabilitazione Santo Stefano

Hidradenitis Suppurativa

Periodontal Diseases

Damien JOLLY

Hidradenitis Suppurativa and Periodontal Diseases

Relationship Between Hidradenitis Suppurativa and Periodontal Diseases

Peridontal disease will be diagnosed based on clinical and radiographic examination

Socio-demographic data (age, sex, etc.) and clinical data (medical history, skin symptoms, etc.) will be collected for all patients included in the study.

These will be investigated using spectroscopy and liquid chromatography coupled with tandem mass spectrometry

CHU de Reims

Association Française pour la Recherche sur l'Hidrosadénite (Financial sponsor)

Association Française d'épargne et de retraite (Financial sponsor)

34 osteopenic postmenopausal women with chronic periodontitis who received calcium (500mg) and vitamin D (250I.U.) supplementation twice a day for 6 months.Scaling and root planing was not done in this group.

34 osteopenic postmenopausal women with chronic periodontitis who received scaling and root planing along with calcium (500mg) and vitamin D (250I.U.) supplementation twice a day for 6 months.

PERIODONTITIS

Osteopenia

calcium (500mg) and vitamin D (250I.U.) was given twice a day for 6 months

calcium (500mg) and vitamin D (250I.U.)

scaling and root planing was done in the test group along with calcium (500mg) and vitamin D (250I.U.)

rheumatic diseases/nicotina

Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in Osteoarthritis

Hidradenitis Suppurativa and Periodontal Diseases

Effect of Periodontitis on Bone Mineral Density in Postmenopausal Women

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