Provided is a process for preparation of a Rhus verniciflua extract, comprising extracting allergen-removed Rhus verniciflua with a soluble solvent, thereby obtaining an extract, subjecting the thus-obtained extract to ultrafiltration to remove high-molecular weigh substances, concentrating and drying the resulting material, thereby obtaining extract powder and irradiating far-infrared to the extract powder, thereby improving anti-cancer activity. The Rhus verniciflua extract prepared according to the process of the present invention exhibits superior anti-cancer activity.

Azi Co., Ltd.

Process for preparation of Rhus verniciflua extracts having excellent anti-cancer activity and anti-cancer pharmaceutical composition containing the same

The present invention relates to Rhus verniciflua Stokes extract having an increased content of an active flavonoid compound through a gas bubbling treatment, a method for preparing the Rhus verniciflua Stokes extract, and a method for converting fustin into fisetin through the gas bubbling treatment of a solution containing fustin. The method for preparing the Rhus verniciflua Stokes extract of the present invention can convert the conventional Rhus verniciflua Stokes extract having high content of fustin and low content of fisetin into a Rhus verniciflua Stokes extract having high content of fisetin. Therefore, the Rhus verniciflua Stokes extract of the present invention can be commercialized into natural anticancer agents, anticancer and cancer prevention food products, and health functional foods due to the excellent bioactivity thereof, and promote the development of relevant industries through the high added-value of Rhus verniciflua Stokes. In addition, the method for converting fustin into fisetin can be applied to other natural substances and be used as a method for enhancing the functionality thereof by increasing the content of a high active flavonoid, thereby becoming an enabling technology that can lead high-functionalization of natural substances.

Park; Sang-Jae

Kim; Kyung-Hee

Shin; Myung-Jae

Lee; Sang-Seok

Kang; Byung-Sik

Choi; Won-Cheol

Kwon; Sung-Pil

AZI Company Ltd.

Rhus verniciflua stokes extract having increased content of active flavonoid compound and method for preparing same

The present invention relates to a method for converting fustin into fisetin through the gas bubbling treatment of a solution containing fustin. Rhus verniciflua Stokes extracts having high content of Fisetin may be used as anticancer agents, anticancer and cancer prevention food products, and health functional foods due to the excellent bioactivity thereof.

Method of converting fustin to fisetin