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15 resultados
Strontium-90 for conjunctival AIDS-related Kaposi's sarcoma: the first case report.
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AIDS-related Kaposi's sarcoma is often treated by local therapy for physically or cosmetically disabling symptoms. We present the first case of a bulbar conjunctival Kaposi's sarcoma lesion to be treated with a strontium-90 ophthalmic applicator. The treatment is simple, effective and well tolerated
[Value of the study of the kinetics of 85 strontium for the classification of osteogenic sarcomas ].
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Because of the polymorphism of osteogenic sarcomas, examination of a biopsy specimen, which is necessarily small, cannot give an accurate evaluation of the differentiation of the whole tumor. Therefore, a test which provides an overall assessment of the functional capacity of the tumor is needed.
Bone sarcoma characteristics and distribution in beagles fed strontium-90.
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A total of 66 primary bone sarcomas were diagnosed in 47 beagles; 43 of these dogs were part of the 403 beagles fed 90Sr and 4 were part of the 162 controls. Multiple primary bone sarcomas were found in 15 of the 47 beagles (32%). The incidence of multiple primary bone sarcoma was restricted to the
Vasoformative non-osteogenic (angio) sarcomas of bone-marrow stroma due to strontium-90.
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In a series of experiments, mainly CBA/H, but also C2H/H, mice aged 3 months were injected intraperitoneally with solutions of 90Sr Cl2, the dose per mouse varying from 7 to 20 muCi, and compared with similar mice treated with 226Ra or 239Pu, discussed elsewhere. In male mice, the commonest tumour
[Osteogenic sarcoma induced by strontium(90) in dogs].
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[The pathogenesis of bone sarcomas in rats following administration of strontium 89 and the effect of strontium 89 on the progeny of these animals].
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Strontium-90 in the long bones of patients with sarcoma.
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[X-ray morphological study of development of bone sarcoma in animals poisoned with radioactive strontium].
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[Effect of roentgen irradiation on the growth, microscopic and submicroscopic structure of bone sarcoma induced with radioactive strontium].
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Strontium promotes osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway.
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Strontium ralenate is a new anti-osteoporosis agent. The cellular and molecular mechanism underlying the anabolic effect of strontium on bone remains to be elucidated. Osteoblasts, the main bone forming cells are known to be derived from bone marrow mesenchymal stem cells (MSCs). The present study
Strontium-89 therapy: strontium kinetics and dosimetry in two patients treated for metastasising osteosarcoma.
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We report a study of strontium kinetics in two patients who received 89Sr therapy for disseminated osteogenic sarcoma, together with estimates of absorbed dose to the principal metastases and to bone marrow. In neither patient did tumour uptake of strontium have a significant effect on whole-body
Radiation-induced meningeal and pituitary tumors in the rat after prenatal application of strontium-90.
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Strontium-90 was inject i.v. into pregnant rats on day 18 post conception (p.c.). This caused a remarkable transplacental radioactivity uptake and accumulation in the ossification centers of the skull basis. The total radiation dose within the surface of these regions was consequently calculated to
Human osteogenic sarcoma: fine structural localization of adenosine triphosphatase.
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The localization of ATPases in 7 osteogenic sarcomas of osteoblastic, chondroblastic and fibroblastic type was investigated at the fine structural level using two types of substrates: one with lead as capturing ion and one with strontium (the latter presumed to reveal sites of Na+-K+-dependent
[Comparative data from radioisotopic and x-ray methods of study in osteogenic group tumors].
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A comparative analysis of the data of roentgenography-angiography, scanning and radiometry with strontium-85 in 54 patients showing osteogenic sarcoma and osteoblastoclastoma has demonstrated a relationship between the quantitative characteristics of the radioactive Sr inclusion and the intensity of
Safety of drugs used in the treatment of osteoporosis.
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A number of drug classes are licensed for the treatment of osteoporosis including bisphosphonates, recombinant human parathyroid hormone (PTH), strontium, hormone replacement therapy (HRT), selective oestrogen receptor modulators (SERMS) and denosumab. This review discusses the safety of
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