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[Presumably false positive serological reactions for syphilis in Central America. III. Relation to the content of protein, albumin and globulin in serum].
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Presumptive false positive serologic reactions for syphilis in Central America. III. Relation to serum protein, albumin, and globulin.
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Serum regulation of in vitro lymphocyte responses in early experimental syphilis.
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Sera from rabbits with early experimental syphilis were tested for their effect on in vitro lymphocyte transformation responses to related specific antigens (sonicated T. pallidum), unrelated specific antigens (sheep erythrocytes), and the T cell mitogen, concanavalin A. Results were compared with
Cerebrospinal fluid treponemal antibodies in untreated early syphilis.
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OBJECTIVE
Examine prevalence and diagnostic utility of cerebrospinal fluid (CSF) treponemal antibodies in early syphilis.
METHODS
Comparison study.
METHODS
Sexually transmitted diseases clinic.
METHODS
Forty patients with untreated early syphilis who underwent lumbar puncture. Fifteen were human
Adequately Treated Remote Syphilis
Does Not Augment
CNS HIV-1 Expression.
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OBJECTIVE
The co-occurence of human immunodeficiency virus (HIV) infection and syphilis may accelerate the course of both infections. We investigated whether remote syphilis infection augmented the activation of central nervous system (CNS) HIV infection and increased the frequency of cerebrospinal
Intrathecal antitreponemal antibody synthesis determination using the INNO-LIA Syphilis Score.
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BACKGROUND
Laboratory detection of intrathecal synthesis of specific antitreponemal antibodies remains a challenge. Traditional syphilis serology is unable to provide a satisfactory result; therefore, several other diagnostic procedures were used to demonstrate central nervous system (CNS)
High HbA1c level is correlated with blood-brain barrier disruption in syphilis patients.
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Diabetes mellitus (DM) and neurosyphilis (NS) may both damage the blood-brain barrier (BBB). It seems that non-neurosyphilis (non-NS) patients with high HbA1c levels are likely to develop into NS. However, the correlation of HbA1c level with BBB disruption in syphilis (non-NS)
Syphilis: test procedures and therapeutic strategies.
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The diagnosis of syphilis is dependent mainly on serological tests. In primary syphilis there is a seronegative period when the diagnosis is dependent on demonstration of Treponema pallidum in lesional exudate. The most widely used screening tests for syphilis are the VDRL and the rapid plasma
A comparison between agar gel electrophoresis and CSF serum quotients of IgG and albumin in neurological disease.
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CSF and serum was obtained from 216 patients with neurological or psychoneurotic symptoms and the concentrations of albumin and IgG were immunologically determined. The IgG/albumin index, calculated as the quotient of the CSF/serum ratios of IgG and albumin was compared with electrophoresis on agar
Congenital syphilis. A study of physical and biochemical aspects.
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Twenty-three infants who had positive cord blood VDRL test results are described. Fourteen had clinical signs of congenital syphilis. All but one of the affected, and only one of the unaffected infants had high immunoglobulin M (IgM) levels. Several affected infants had low immunoglobulin G (IgG)
[Syphilis antibodies in the cerebrospinal fluid and their diagnostic significance (author's transl)].
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Serum and CNS fluid from 45 patients was tested to provide serum/CNS fluid ratios for IgG, albumin and TPHA titre, as well as protein ratios after Delpech and Lichtblau. Local production of specific antibody in the CNS was demonstrated in 10 of 11 patients with a clinical diagnosis of active
Central nervous system involvement in early syphilis. Part 1. Intrathecal immunoglobulin production.
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The immunological activity in the cerebrospinal fluid (CSF) was studied in 47 patients with early syphilis. The immunoglobulin production within the central nervous system (CNS) was estimated by analysing immunoglobulin G and albumin in CSF and serum and constructing an IgG index according to
Effect of early and late syphilis on central nervous system: cerebrospinal fluid changes and neurological deficit.
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Neurological examination and investigation of the cerebrospinal fluid (CSF) was performed on 24 patients with early and 180 patients with late syphilis. In 21 (12%) patients with late syphilis positive CSF treponemal test results and neurological deficits suggestive of symptomatic neurosyphilis were
Isolation and preliminary characterization of circulating immune complexes from rabbits with experimental syphilis.
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Immune complexes isolated from sera of rabbits with experimental, disseminated syphilis were found to have sedimentation coefficients greater than 19s. By radioimmunoblot assays, materials precipitated with 2.5% polyethylene glycol or chromatographed on DEAE-Affi-Gel Blue were found to contain
Syphilis masquerading as focal segmental glomerulosclerosis.
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A patient referred to the genitourinary clinic for positive syphilis serology was found to have symptoms and signs of nephrotic syndrome. A renal biopsy showed focal segmental glomerulosclerosis (FSGS). Doxycycline 200 mg twice daily for 28 days coincided with considerable decrease in proteinuria
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