thalassemia/carbohydrate

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β-thalassemia minor, carbohydrate malabsorption and histamine intolerance.

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Background: β-thalassemia minor is characterized by reduced β-haemoglobin chain synthesis and sometimes mild anaemia, although carriers of β-thalassemia minorare usually clinically asymptomatic.Nonspecific abdominal complaints may be caused by gastrointestinal carbohydrate malabsorption (lactose and

Carbohydrate metabolism and pancreatic islet-cell function in thalassemia major.

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To investigate the development of diabetes mellitus in patients with thalassemia major, plasma glucose and immunoreactive insulin (IRI) levels following oral glucose and intravenous tolbutamide and glucose disappearance rates following intravenous insulin were measured in 10 patients before and

Carbohydrate homeostasis and pancreatic islet cell funtion in thalassemia.

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[A correlative study of carbohydrate metabolism and blood ferritin in thalassemia patients].

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[FTIR-HATR to identify beta-thalassemia and its mechanism study].

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Fourier transform infrared spectroscopy (FTIR) associated with horizontal attenuated total reflectance (HATR) was firstly used to diagnose beta-thalassemia patients. With excellent linearity (r = 0.997) and reproducibility (RSD < 4%), FTIR-HATR shows an order-of-magnitude increase in IR absorption

Body Composition in Egyptian Children With Transfusion-dependent Thalassemia: The Impact of Nutrition and Metabolic Profile.

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Growth failure is a common complication in children with beta-thalassemia major (β-TM) that has persisted despite major treatment advances. It could stem from malnutrition, especially in those who live in poor countries and who have inadequate nutrient

The Effects of Postprandial Resistance Exercise on Blood Glucose and Lipids in Prediabetic, Beta-Thalassemia Major Patients.

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Insulin resistance and diabetes mellitus are common consequences of iron overload in the pancreas of beta-thalassemia major (BTM) patients. Moreover, postprandial blood glucose elevations are linked to major vascular complications. The purpose of this study was to investigate the effects of a bout

Association of iron overload and oxidative stress with insulin resistance in transfusion-dependent beta-thalassemia major and beta-thalassemia/HbE patients.

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BACKGROUND Beta-thalassemia causes a severe hemolytic anemia in patients necessitating frequent transfusions leading to iron overload and endocrine complications, especially diabetes mellitus. We tried to determine the change or effect on carbohydrate physiology and oxidation markers and the

Glutaric acidemia type II patient with thalassemia minor and novel electron transfer flavoprotein-A gene mutations: A case report and review of literature.

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Glutaric acidemia type II (GAII), also known as multiple acyl-CoA dehydrogenase deficiency, is an autosomal recessive inborn error of amino acid and fatty acid metabolism. We report a case of GAII with novel electron transfer flavoprotein (ETF)-A mutations in a 2-year-old female with thalassemia

Pleiotropic actions of iron balance in diabetes mellitus.

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As an essential element, iron plays a central role in many physiological processes, including redox balance, inflammation, energy metabolism, and environment sensing. Perturbations in iron homeostasis are associated with several conditions, including hyperglycemia and diabetes, both of which have

IBEM in Thailand.

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The incidence of IBEM in Thailand is yet unknown, however, by estimation it is generally accepted to be 1 in 5,000. From a recent survey in 7 medical schools from different parts of the country and a largest pediatric hospital in Bangkok, we found numerous cases of IBEM nationwide. These are amino

Antigens protected functional red blood cells by the membrane grafting of compact hyperbranched polyglycerols.

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Red blood cell (RBC) transfusion is vital for the treatment of a number of acute and chronic medical problems such as thalassemia major and sickle cell anemia. Due to the presence of multitude of antigens on the RBC surface (~308 known antigens), patients in the chronic blood transfusion therapy

Inherited metabolic disorders in Thailand--Siriraj experience.

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The incidence of inborn errors of metabolism (IEM) in Thailand is yet unknown. However, by estimation it is generally accepted to be 1 in 5,000. From a survey in 7 medical schools from different parts of the country and a large pediatric hospital in Bangkok, we found numerous cases of IEM

Demonstration of a natural antigalactosyl IgG antibody on thalassemic red blood cells.

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A modified antiglobulin test, based on the high affinity between the Fc portion of the red blood cell (RBC) bound IgG and the Fc receptor on the myeloid cell K-562, was utilized for demonstration of immunoglobulins (Ig) on thalassemic RBC. Ig was found on the RBC of 73 out of 80 patients with

[Nutritional habits of homozygote beta-thalassemic subjects].

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An investigation on eating habits of a group of 40 patients with beta-thalassemia major has been carried out mainly to evidentiate iron intake whose absorption is strikingly increased in this disease. Questionnaires were used to obtain information. Daily food intake, the mean consumption of various

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