west/hypoxia

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Career perspective: John B West.

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I have been fortunate to work in two areas of extreme physiology and medicine: very high altitude and the microgravity of spaceflight. My introduction to high altitude medicine was as a member of Sir Edmund Hillary's Silver Hut Expedition in 1960-1961 when a small group of physiologists spent the

A tribute to John Burnard West.

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John West is well known to the "Hypoxia" community for his many contributions to the physiology and Pathophysiology of high altitude and for his leadership of the 1981 American Medical Research Expedition to Everest. He is known to the wider medical world for his researches into respiratory

[West syndrome: aetiology, therapeutic options, clinical course and prognostic factors].

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BACKGROUND West syndrome is an age-specific form of epilepsy that associates infantile spasms, hypsarrhythmia and a delay in or the complete stoppage of psychomotor development, although this last case is not essential. OBJECTIVE To define the profile of West syndrome in our environment by taking

No association of hypoxia inducible factor-1α gene polymorphisms with breast cancer in North-West Indians.

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BACKGROUND Hypoxia inducible factor-1 alpha (HIF-1α) is the key regulator of cellular responses to hypoxia and plays a central role in tumour growth. Presence of Single nucleotide polymorphisms (SNPs) in the critical regulatory domains of HIF-1α may result in the overexpression of the protein and

West syndrome: early remission is not assurance of normal final outcome.

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BACKGROUND West syndrome (WS), an age-specific epilepsy of infancy and early childhood, considered of poor prognosis, may have remission. With the objective of describing the clinical features, treatment and outcome of the children with WS followed in a Latin American country, we devised a

East meets West: a comparison of eastern block/western aeromedical practices.

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Under the auspices of the European Command (EUCOM) Military-to-Military Exchange Program, the authors participated in 13 trips to visit aeromedical facilities of nine Eastern European nations (Albania, Belarus, Bulgaria, Czech Republic, Hungary, Lithuania, Poland, Romania, and Slovakia). In

Submicroscopic infection of placenta by Plasmodium produces Th1/Th2 cytokine imbalance, inflammation and hypoxia in women from north-west Colombia.

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BACKGROUND A large-scale study was set up in order to study the epidemiology, clinical aspects, and immunopathology of gestational and placental malaria in north-west Colombia. In this region, recent reports using a qPCR technique, confirmed frequencies of infection, by Plasmodium falciparum or

The spectrum of hypoxaemia in children admitted to hospital in The Gambia, West Africa.

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OBJECTIVE Hypoxia predicts mortality in children with acute lower respiratory infections (ALRIs). We investigated the prevalence and predictive value of hypoxia in ALRI and other acute infectious diseases. METHODS We studied the spectrum of hypoxaemia in 4,047 children admitted to a tertiary

Assessment of hypoxic stress in 44 women with breast cancer in the West Algeria.

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OBJECTIVE The objective of this study was to evaluate the expression of hypoxia-inducible transcription factor 1α (HIF1α) protein profile among women with breast cancer in a population of western Algerian and to correlate the intensity of this expression with prognosis histological grade Scarff

Assessing and managing the risks of hypoxia in transitional waters: a case study in the tidal Garonne River (South-West France).

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The Gironde estuary (S-W France) is one of the largest European macrotidal estuaries. In the tidal Garonne River, its main tributary, episodes of low (<5 mg L-1) to hypoxic (<2 mg L-1) dissolved oxygen (DO) concentrations have been occasionally recorded close to Bordeaux, about 100 km from the

Effects of bottom-water hypoxia on sediment bacterial community composition in a seasonally hypoxic enclosed bay (Omura Bay, West Kyushu, Japan).

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The bacterial community strongly drives carbon and other biogeochemical cycles in marine sediment. However, little is known about the impact of dissolved oxygen (DO) availability on bacterial community composition. To fill this gap, we examined diversity, richness and structure of the bacterial

[Pneumococcal pneumonia with bacteremia in adults: a descriptive study from the north-west of Spain].

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OBJECTIVE Analysis of adults patients (> 15 years of age) with Bacteremic Pneumococcal Pneumonia (BPP), in the Hospital Complex of Pontevedra. METHODS 83 cases of BPP were studied in the last 6 years (1995-2000). RESULTS There were 57 men and 26 women. The overall mean age was 56 year-old; in those

Pediatric anesthesia in developing countries: experience in the two main university hospitals of Benin in West Africa.

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OBJECTIVE To describe the practice of pediatric anesthesia in the main University Hospitals in Benin. METHODS We conduct a retrospective study involving 512 children at the 'Centre National Hospitalier et Universitaire' and the 'Hôpital de la Mère et de l'Enfant Lagune' in Cotonou. All children less

Clinical, bronchoscopic, histopathologic, diagnostic imaging, and arterial oxygenation findings in West Highland White Terriers with idiopathic pulmonary fibrosis.

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BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a chronic, interstitial lung disease primarily affecting West Highland White Terriers (WHWTs). OBJECTIVE To describe the clinicopathological and diagnostic imaging features in WHWTs with IPF. METHODS Twelve WHWTs with IPF and 14 healthy control

Proportion and Associated Factors of Nonreassuring Fetal Heart Rate Patterns in Finote Selam Primary Hospital, North West Ethiopia

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Introduction: Nonreassuring fetal heart rate patterns (NRFHRP) suggest fetal conciliation or a deteriorating ability to handle the stress of labor. Nearly half of stillbirths occurring worldwide are due to hypoxia which is primarily

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