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Epidemic (human immunodeficiency virus-related) Kaposi's sarcoma in West African women.
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BACKGROUND
Most patients infected with human immunodeficiency virus (HIV) experience skin disease at some stage of their illness, either as a presenting feature or as a later manifestation. Different dermatoses may coexist during the course of the infection, and the unusual nature of the skin
Ifosfamide in the treatment of soft-tissue sarcomas: experience at the West German Tumor Center, Essen.
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The response of ifosfamide-based chemotherapeutic regimens was retrospectively analyzed in adult patients with advanced soft-tissue sarcoma who were treated at the West German Tumor Center, Essen, between 1978 and 1990. Single-agent ifosfamide was given either in split doses of 60-80 mg/kg by 4-h
Male breast cancer: 22 case reports at the National Hospital of Niamey-Niger (West Africa).
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BACKGROUND
Male breast cancer (MBC) is rare. The objective of the study is to report clinicopathological characteristics, treatment patterns, and outcomes of MBC.
METHODS
This study, which includes two parts (retrospective and prospective), focused on all hospitalized male patients with breast
Fifty years of paediatric malignant bone tumours in the West Midlands, UK, 1957-2006: incidence, treatment and outcome.
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Malignant bone tumours in the paediatric age group (0-14 years) are uncommon; various aetiological theories exist and few reports of incidence, age and sex distributions have been published. We examined the incidence of childhood malignant bone tumours in one large single region of the UK over an
[Multidrug chemotherapy of osteogenic sarcoma (author's transl)].
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Osteogenic sarcoma may be treated effectively by radical surgical removal of the primary tumor and combined chemotherapy, including Adriamycin and high dose Methotrexate. In order to render any protocol a safe procedure, strict precautions are required to avoid drug toxicity. We present a protocol,
Conceptual emergence of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) as an oral herpesvirus.
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Recognition of the various clinico-epidemiologic forms of Kaposi's sarcoma, a disease putatively caused by an infectious agent, did not provide ready clues as to how that agent might be transmitted, although fecal and sexual routes were implicated. Application of serologic and genome-detection
An atypical aggressive Kaposi's sarcoma in a HIV-negative bisexual man.
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We describe a case of Kaposi's sarcoma in a previously healthy 35-year-old bisexual West Indian man of African descent who was seronegative for the human immunodeficiency virus (HIV) and human T-cell lymphotropic virus-1 (HTLV-1) and who presented with extensive mucocutaneous lesions, weight loss,
Kaposi sarcoma, oral malformations, mitral dysplasia, and scoliosis associated with 7q34-q36.3 heterozygous terminal deletion.
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Chromosome 7 germline macrodeletions have been implicated in human congenital malformations and developmental delays. We herein report a novel heterozygous macrodeletion of 7q34-q36.3 in a 16-year-old girl originally from West Indies. Similar to previously reported cases of germline chromosome 7q
Biology and therapy of epidemic Kaposi's sarcoma.
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Kaposi's sarcoma, once a rarely seen neoplasm in the West, now occurs in an epidemic fashion in association with acquired immune deficiency syndrome (AIDS). The pathogenesis of Kaposi's sarcoma is still unclear but it appears to be an endothelial neoplasm. Its clinical presentation may be quite
Giant primary synovial sarcoma of the anterior mediastinum: A case report and review of literature.
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Primary synovial sarcoma is a very rare tumor of the mediastinum, which is unreported in the entire subcontinent of West Africa, and presents daunting challenges from diagnosis to management with lack of standard management strategies. We present a case of primary monophasic synovial sarcoma of the
[Analysis of 19 cases of primary pulmonary sarcoma].
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OBJECTIVE
Primary pulmonary sarcoma (PPS) is a rare malignant tumor that originates from the mesenchymal tissue of the lungs. PPS is often easily misdiagnosed. This study aims to explore the clinical characteristics of PPS and provide a more comprehensive reference for the early diagnosis and
Clinical presentation of non-HIV Kaposi Sarcoma.
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Kaposi Sarcoma (KS) is a rare entity. In the north west of Pakistan and Afghanistan, we mostly come across non-HIV related Kaposi sarcoma as Human Immunodeficiency Virus (HIV). Infections are rare in this part of the world. Here, we present a case of a non-auto Immunodeficiency Disease (AIDS)
Is the anti-sarcoma and anti-viral cytokine "plasma factor" a novel chicken Y-box protein?
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A line of research beginning in the early 1960s with the observation that West Nile virus and, later, several strains of rabies virus could inhibit the development of the Rous sarcoma virus-induced tumor in the wing-web of chicken (a "sarcoma-blockade") eventually culminated in the characterization
Adult genitourinary sarcoma: Clinical characteristics and survival in a series of patients treated at a high-volume institution.
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OBJECTIVE
To report our institutional experience in the management of adult genitourinary sarcoma.
METHODS
This was a retrospective analysis of data on adult genitourinary sarcoma treated at the West China Hospital, Sichuan University, Chengdu, Sichuan, China from 1985 to 2010. Clinicopathological
Synovial sarcoma of childhood and adolescence. Report of the German CWS-81 study.
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BACKGROUND
Synovial sarcoma is the third most common pediatric soft tissue tumor. It requires an aggressive approach to achieve a cure. However, optimal treatment modalities adapted to disease extension and histologic variants have not been determined because there is little information about
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