Pest Management Science 2019-Oct
Compounds from the root of Pueraria peduncularis (Grah. ex Benth.) Benth. and their antimicrobial effects.
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RESULTS
The root methanol extract inhibited the mycelial growth of the five tested phytopathogens to different degrees. Among these phytopathogens, the inhibitory effect was greatest against R. solani, with an EC50 value of 324.72 mg L-1 . Eight compounds were subsequently isolated and identified from P. peduncularis. Among them, puercarpan A and medicarpin showed strong fungicidal activity, with MIC values against Rhizoctonia solani of 1.6 and 6.25 mg L-1 , respectively. Puercarpan A is a new compound, and its structure was established as (6aR,6bS,11aR)-6b-hydroxy-3-methoxypterocarpan-10-ene-7-one.