Glutathione peroxidase activity in serum during acute myocardial infarction and unstable angina pectoris.

We studied GSH-Px enzyme activity in serum after acute myocardial infarction (AMI) and unstable angina pectoris (UAP). The study included 15 patients with AMI and 9 patients with UAP. Serum GSH-Px activity in the AMI group (0.992 +/- 0.071) (IU/ml) was higher than that of the UAP group. Serum GSH-Px activity was established as 0.683 +/- 0.110 (IU/ml) in UAP and 1.012 +/- 0.121 (IU/ml) in 10 healthy subjects (p < 0.0005). We suggest that measurement of serum GSH-Px activity together with other enzyme tests such as CK-MB, LDH, GOT, etc. can be helpful in the differentiation of AMI from UAP.