adonis palaestina/glycoside

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Aestivalosides A-L, twelve pregnane glycosides from the seeds of Adonis aestivalis.

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Eight adonilide (14,20α-epoxy-3β,20-dihydroxy-14β-pregn-5-en-18-oic acid γ-lactone) glycosides, named aestivalosides A-H, and four glycosides of the adonilide derivatives, named aestivalosides I-L, were isolated from the MeOH extract of seeds of Adonis aestivalis. Aestivalosides A-L were previously

Introduction of Adonis aestivalis as a new source of effective cytotoxic cardiac glycoside.

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Cardiac glycosides are used for treatment of irregular heartbeats, cardiac arrhythmia and congestive heart failures. In this research, digitoxin as a cardiac glycoside was identified and isolated for the first time in the world from Adonis aestivalis and investigated for its cytotoxic activity

Amurensiosides L-P, five new cardenolide glycosides from the roots of Adonis amurensis.

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Five new cardenolide glycosides, amurensiosides L-P (1-5), were isolated from the roots of Adonis amurensis. Their structures were determined based on extensive spectroscopic analysis, including two-dimensional (2D) NMR data, and on the results of hydrolytic cleavage. Compounds 1-5 were evaluated

[Qualitative and Quantitative HPLC-Analysis of Cardiac Glycosides].

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An analytical pathway for identification of cardenolides from Adonis, Convallaria, Strophanthus and Lophopetalum extracts by HPLC is described. Structure-retention-relationships between cardiac glycosides and HPLC-separations of Strophanthus gratus, Strophanthus kombé and Adonis vernalis drugs are

Detection of poisoning by plant-origin cardiac glycoside with the Abbott TDx analyzer.

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Cardiac glycoside poisoning caused by ingestion of plant material is common in tropical and sub-tropical areas. In evaluating the use of the Abbott TDx Digoxin II assay to detect such cases of poisoning, we found it a rapid and convenient method for confirming the ingestion of glycosides from the

Amurensiosides A-K, 11 new pregnane glycosides from the roots of Adonis amurensis.

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Five new pregnane tetraglycosides, amurensiosides A-E (1-5), two new pregnane hexaglycosides, amurensiosides F (6) and I (9), two new 18-norpregnane hexaglycosides, amurensiosides G (7) and H (8), and two new pregnane octaglycosides, amurensiosides J (10) and K (11), were isolated from the MeOH

[The cardenolide glycosides of Adonis mongolica Sim].

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A NEW GLYCOSIDE OF ADONIS VERNALIS.

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ACTIVITIES OF NEWER GLYCOSIDES OF ADONIS VERNALIS L.

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[Strophanthidin digitaloside and strophanthidin 6-deoxyguloside, two new cardenolide glycosides from Adonis vernalis L (author's transl)].

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[On the combined use of adonis vernalis with cardiac glycosides and strophanthin derivatives in treating patients with circulatory insufficiency].

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Cardiovascular effects of Adonis aestivalis in anesthetized sheep.

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Adonis aestivalis (summer pheasant-eye) is an annual plant with a crimson flower, distributed in southern Europe and Asia. The plant has large buttercup-like blossoms and soft, fern-like leaves. It blooms in spring and is often found as a weed in cereal fields. Like other Adonis spp., the plant

New cardenolides from the seeds of Adonis aestivalis.

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Chemical investigation of the seeds of Adonis aestivalis has led to the isolation of a new cardenolide (3β,5α,14β,17β-tetrahydroxycard-20,22-enolide) (1), two new glycosides (2, 3) of 1, and a new strophanthidin hexaglycoside (4), together with a known compound, strophanthidin

Adonis microcarpa (pheasant's eye) toxicity in pigs fed field pea screenings.

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Seed of Adonis microcarpa (pheasant's eye) fed at 5.6 g/kg of the diet induced virtually total feed refusal within 3 d in growing and finishing pigs. It also caused vomiting, rapid and shallow breathing and death in a minority. These effects were probably caused by cardiac glycosides whose structure

Adonis sp., Convallaria sp., Strophanthus sp., Thevetia sp., and Leonurus sp. - Cardiotonic Plants with Known Traditional Use and a Few Preclinical and Clinical Studies.

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Plants have been always a fruitful source of active metabolites against many human disorders, where cardiovascular (CV) diseases have been one of the major health problems all over the world. There are some clinically proved medicinal plants with cardioprotective effects such as Crataegus monogyna

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