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Peptide sequence that promotes tumor invasion

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BACKGROUND The genetic basis of cancer dissemination, also known as metastasis, has been subject to intense debate. Metastasis genes have been identified as stress response genes, which in cancer are deregulated on the levels of aberrant expression and splicing. Osteopontin is a cytokine that is

Peptide sequence that promotes tumor invasion

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND The genetic basis of cancer dissemination, also known as metastasis, has been subject to intense debate. Metastasis genes have been identified as stress response genes, which in cancer are deregulated on the levels of aberrant expression and splicing. Osteopontin is a cytokine that is

Methods for the suppression of neu mediated tumors by the adenoviral EIA gene

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The present invention relates to methodology and associated genetic constructs for the suppression of oncogene-mediated, transformation, tumorigenesis and metastasis. In particular, this invention relates to the suppression of oncogenesis that is mediated by the HER-2/c-erb B-2/neu oncogene, an

Methods for the suppression of neu mediated tumors by adenoviral E1A and SV40 large T antigen

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A. Field of the Invention The present invention relates to methodology and associated genetic constructs for the suppression of oncogene-mediated, transformation, tumorigenesis and metastasis. In particular, this invention relates to the suppression of oncogenesis that is mediated by the HER-2/c-erb

Methods for the suppression of neu mediated phenotype in tumors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION A. Field of the Invention The present invention relates to methodology and associated genetic constructs for the suppression of oncogene-mediated, transformation, tumorigenesis and metastasis. In particular, this invention relates to the suppression of oncogenesis that is

Methods for the suppression of neu mediated tumors by adenoviral E1A and SV40 large T antigen

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION A. Field of the Invention The present invention relates to methodology and associated genetic constructs for the suppression of oncogene-mediated, transformation, tumorigenesis and metastasis. In particular, this invention relates to the suppression of oncogenesis that is

Bone and prostate-derived protein factors affecting prostate cancer growth, differentiation, and metastasis

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates generally to the field of cancer and also to polypeptides with growth-promoting activities. The invention is particularly directed to the identification of growth factors, primarily from bone and prostate tissues,

Targeting metabolic enzymes in human cancer

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CROSS-REFERENCE TO RELATED APPLICATION This application is a national stage filing under 35 U.S.C. .sctn.371 of international application PCT/SG2011/000400, filed Nov. 11, 2011, which claims priority to Singapore Application No. 201008288-1, filed Nov. 11, 2010, the contents of all of which are

Nucleophosmin/B23-binding peptide to inhibit tumor growth and regulate transcriptional activity of p53

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to tumors. More specifically, the present invention discloses a method of inhibiting tumor growth and up-regulating transcriptional activity of p53 by utilizing Nucleophosmin/B23-binding peptide. 2. Description of
FIELD OF THE INVENTION This invention pertains generally to products and techniques for testing the resolution capabilities of nuclear magnetic resonance (NMR) imaging equipment and particularly to imaging processes in which hydrogen is the monitored nucleus. BACKGROUND OF THE INVENTION The early

Isolated polypeptide erbB-3, related to the epidermal growth factor receptor and antibody thereto

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FIELD OF THE INVENTION The present invention relates to genes which encode novel proteins related to a family of receptor proteins typified by two related membrane spanning tyrosinc kinases: the Epidermal Growth Factor receptor (EGFR), which is encoded by the erbB gene, the normal human counterpart

Recombinant DNA encoding an epidermal growth factor receptor related protein

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FIELD OF THE INVENTION This invention relates to the epidermal growth factor related proteins, polynucleotides encoding these proteins and methods for using these proteins. The cellular machinery involved in mitogenesis is complex, and not yet fully understood. In general, receptors present on the

Isolation and characterization of a rat epidermal growth factor related protein

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FIELD OF THE INVENTION This invention relates to the epidermal growth factor related proteins, polynucleotides encoding these proteins and methods for using these proteins. The cellular machinery involved in mitogenesis is complex, and not yet fully understood. In general, receptors present on the

Capsules for oral preparations and capsule preparations for oral administration

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FIELD OF THE INVENTION 1. Background of the Invention This invention relates to capsules for preparations for oral administration and also to capsule preparations for oral administration using said capsules. More particularly, this invention relates to capsules being able to be administered orally

p40 protein acts as an oncogene

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TECHNICAL FIELD OF THE INVENTION This invention is related to the field of cancer diagnostics and therapeutics. BACKGROUND OF THE INVENTION p53 is the most commonly inactivated gene in human cancer and loss of critical p53 pathways are central to tumorigenesis.sup.1,2. The p53 protein binds specific
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