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FIELD OF THE INVENTION
This invention relates generally to the field of human genetics. More specifically, the invention relates to human germline mutations or polymorphisms in the ACP1 gene, methods and materials used to isolate and detect said mutations or polymorphisms and further to their use in
FIELD OF THE INVENTION
The present invention relates to the use of alkaline and acid phosphatase inhibitors in the treatment of neurological disorders. More particularly, the present invention relates to the use of various specific phosphatase inhibitors in the treatment of .beta.-amyloid toxicity
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention concerns a method for the treatment of amyloidosis associated with Alzheimer's disease by administering to a patient an effective amount of at least one agent that modulates or affects the phosphorylation of proteins in
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a .sctn.371 national stage of PCT International Application No. PCT/IB2013/051916, filed Mar. 11, 2013, claiming priority of Portuguese Patent Application No. 106202, filed Mar. 9, 2012, the contents of each of which are hereby incorporated