Leht 1 alates 78 tulemused
BACKGROUND OF THE INVENTION
The present invention relates to the use of saturated monocyclic or bicyclic terpenes for the treatment of inflammatory diseases. It is particularly concerned with the use of saturated monocyclic terpenes for the treatment of steroid-requiring inflammatory diseases
Arachidonic acid, and other twenty carbon "essential" fatty acids having at least three double bonds, can be used to make prostaglandins (for a review, see, e.g., Goodman and Gilman's The Pharmacological Basis of Therapeutics (A. Goodman Gilman et al., eds.), Pergamon Press, New York (1990), pp.
FIELD OF THE INVENTION
The present invention relates generally to the fields of lipid metabolism and dietary supplementation. More particularly, it concerns compositions and methods for controlling or reducing symptoms of inflammation or inflammatory conditions that include the use of unsaturated
FIELD
The invention relates to compositions and methods for treating, moderating, and preventing inflammation. Specifically, the invention relates to compositions useful for inhibiting the formation of arachidonic acid, which is a precursor of pro-inflammatory eicosanoids. The invention also relates
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of lipid metabolism and dietary supplementation. More particularly, it concerns compositions and methods for inhibiting an increase in serum arachidonic acid of a mammal to which
FIELD OF THE INVENTION
The invention relates to the area of inflammatory mediators. The invention is based on the discovery that blocking a key enzyme responsible for arachidonate movement (or remodelling), Coenzyme A-independent transacylase (CoA-IT), inhibits the production of lipid mediators
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates generally to compositions and methods for preventing or treating inflammatory bowel disease and particularly to the use of docosahexaenoic acid for preventing or treating feline inflammatory bowel disease.
2. Description of
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates generally to compositions and methods for presenting or treating inflammatory bowel disease and particularly to the use of docosahexaenoic acid for preventing or treating feline inflammatory bowel disease.
2. Description of
Arachidonic acid, and other twenty carbon "essential" fatty acids having at least three double bonds, can be used to make prostaglandins (for a review, see, e.g., Goodman and Gilman's The Pharmacological Basis of Therapeutics (A. Goodman Gilman et al., eds.), Pergamon Press, New York (1990), pp.
SEQUENCE LISTING
This application includes a Sequence Listing submitted electronically as a text file named "17738US_sequencelisting.txt," created on Nov. 5, 2010, with a size of 42 kb. The sequence listing consists of 43 sequences and is incorporated by reference.
FIELD OF INVENTION
The invention
FIELD OF INVENTION
The invention relates generally to accelerating or enhancing bone formation or fracture healing by modulating an arachidonic acid metabolic or signaling pathway, in particular by using inhibitors of 5-lipoxygenase activity.
BACKGROUND OF THE INVENTION
Bone fractures are a common
BACKGROUND INFORMATION
The present invention relates to the multiple modes of inhibition by a drug molecule of an enzymatic pathway postulated for a disease state. In particular the invention relates to new chemical compounds that inhibit the various enzymes in the arachidonic acid pathway
This invention relates to heterocyclic compounds and their preparation and to the use of such compounds of pharmaceutical formulations thereof in medicine in a mammal, including man, as e.g. anti-inflammatory or anti-allergic agents or as agents in the prevention of tissue rejection.
Accordingly,
The present invention relates to novel DNA and peptide sequences encoding a family of phospholipase A.sub.2 enzymes, which are useful in methods for detecting the anti-inflammatory potential of various chemical agents. The invention also details methods for making the novel peptides, and methods for
The present invention relates to methods and compositions that provide for the diagnosis and treatment of prostatic intraepithelial neoplasia. A particular aspect of the invention relates to methods and compositions containing compounds which inhibit phospholipase A.sub.2, particularly those that