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The present invention is concerned with indolin-2-one derivatives of general formula
##STR00002## wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from
##STR00003## or the amine group --NR.sup.1R.sup.2 may form together with two neighboring carbon atoms
The present invention is concerned with indolin-2-one derivatives of general formula
##STR00002## wherein A is phenyl or a five or six membered heteroaryl group, containing one or two N atoms, selected from
##STR00003## or the amide group --C(O)--NR.sup.1R.sup.2 may form together with two
The present invention is concerned with indolin-2-one derivatives of general formula
##STR00004## wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from
##STR00005## or the oxygen atom may form together with two neighboring carbon atoms from the group A
The present invention is concerned with indolin-2-one derivatives of general formula
##STR00004## wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from
##STR00005## R.sup.1 is S(O).sub.2lower alkyl, S(O).sub.2NR.sup.4R.sup.5, S(O).sub.2cycloalkyl,
1. FIELD OF THE INVENTION
This invention relates to methods and pharmaceutical compositions for aiding smoking cessation, treating nicotine addiction, and pain, including chronic pain, neuropathetic pain and reflex sympathetic dystrophy, and other disorders.
2. BACKGROUND OF THE INVENTION
Many
FIELD OF THE INVENTION
This invention relates to methods and pharmaceutical compositions for aiding smoking cessation, treating nicotine addiction, and pain, including chronic pain, neuropathetic pain and reflex sympathetic dystrophy, and other disorders.
BACKGROUND OF THE INVENTION
Many organic
FIELD OF THE INVENTION
The present invention relates to new therapeutically active and selective inhibitors of the enzyme dipeptidyl peptidase-IV (hereinafter "DPP-IV"), pharmaceutical compositions comprising the compounds and the use of such compounds for treating diseases that are associated with
FIELD OF THE INVENTION
The present application is directed to the use of droxidopa, alone or in combination with one or more additional components, for the treatment of Central Sensitivity Syndromes, such as fibromyalgia.
BACKGROUND
Droxidopa is a known synthetic amino acid precursor of