12 tulemused
Kawasaki disease (KD) is an acute febrile vasculitic syndrome of unknown etiology that preferentially affects the coronary artery. Interleukin-10 (IL-10) is a key proinflammatory cytokine, and a polymorphism near the major transcriptional start site of the IL-10 gene was shown to influence IL-10
Yılmazer MM, Özdemir R, Meşe T, Küçük M, Öner T, Devrim İ, Bayram N, Güven B, Tavlı V. Kawasaki disease in Turkish children: a single center experience with emphasis on intravenous immunoglobulin resistance and giant coronary aneurysms. Turk J Pediatr 2019; 61: 648-656. Prompt diagnosis and the
BACKGROUND
Coronary artery lesions (CALs) are known to be the main complication in children with Kawasaki disease (KD). Instead of intravenous immunoglobulin (IVIG), corticosteroid therapy has been accepted to be used for children with KD who are unresponsive to IVIG. This study aimed to evaluate
BACKGROUND
Increased microvascular permeability is an initial step of Kawasaki disease (KD). We reported that vascular endothelial growth factor (VEGF) might play a role in the vascular leakage of KD. In fatal KD, plasma leakage was extensively documented at VEGF-positive microvessels. Increases in
BACKGROUND
Inadequate diagnostic criteria in incomplete Kawasaki disease (KD) patients may lead to misdiagnosis and delayed treatment. However, the risk of coronary artery aneurysm in these patients remains uncertain.
OBJECTIVE
To investigate differences in clinical, laboratory and echocardiographic
Study design: ICD codes were used to identify children with Kawasaki disease admitted to a tertiary Southeast U.S. center. Subjects diagnosed and treated according to AHA criteria were included. Demographic, laboratory, clinical and
OBJECTIVE
To study the clinical and laboratory features of children with Kawasaki disease (KD) aged >5 years.
METHODS
A retrospective analysis was performed for the clinical data of 250 elderly children (aged >5 years) who were diagnosed with KD or incomplete KD (divided into 5-9 years and >9 years
BACKGROUND
Kawasaki disease (KD) is an acute systemic vasculitis with unknown etiology. The diagnosis of KD depends on clinical manifestations. The prevalence of coronary artery abnormality (CAA) is 11.0% and results in cardiac sequelae, such as myocardial infarction or coronary aneurysm, which are
Kawasaki disease (KD) is characterized by marked activation of immune system and generalized vasculitis including coronary arteritis, and the intravenous gammaglobulin therapy is recommended as the first line of the choices. However, in some fulminant cases the coronary arteritis progresses rapidly
BACKGROUND
Kawasaki disease (KD) is a febrile systemic vasculitis of unknown etiology and the main cause of acquired heart disease among children in the developed world. To date, abdominal involvement at presentation is not recognized as a risk factor for a more severe form of the
BACKGROUND
Cardiac lesions, such as coronary dilatation, aneurysms, narrowing, myocardial infarction, and valvular lesions, sometimes occur in Kawasaki disease, but most studies have only evaluated cardiac lesions in the later phase of the disease. This study was undertaken to clarify the related