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dyspepsia/oksendamine

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Five-membered ring systems with bonded imidazolyl ring substituents

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
This invention relates to a class of 5-membered heterocyclic compounds having at least one heteroatom, which are useful in the treatment of psychotic disorders (e.g. schizophrenia and mania); anxiety; alcohol or drug withdrawal or dependence; pain; gastric stasis; gastric dysfunction (such as occurs

Benzisoxazole derivatives

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION This invention relates to benzisoxazole derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment

Indazole derivatives

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION This invention relates to Indazole Derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of

Oxyindole derivatives

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION This invention relates to Oxyindole Derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of

Benzimidazolone compounds having 5-HT4 receptor agonistic activity

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
TECHNICAL FIELD This invention relates to novel benzimidazolone compounds. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, a method of treatment and use comprising the above compounds for the treatment of
This invention relates to a class of spirocyclic compounds which are useful in the treatment of psychotic disorders (e.g. schizophrenia and mania); anxiety; alcohol or drug withdrawal or dependence; pain; gastric stasis; gastric dysfunction (such as occurs with dyspepsia, peptic ulcer, reflux

Physiologically active 1,2,4,-oxa- and thiadiazoles

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
This invention relates to a class of 5-membered heterocyclic compounds having at least one heteroatom, which are useful in the treatment of psychotic disorders (e.g. schizophrenia and mania); anxiety; alcohol or drug withdrawal; pain; gastric stasis; gastric dysfunction (such as occurs with
This invention relates to a class of 5-membered heterocyclic compounds having at least one heteroatom, which are useful in the treatment of psychotic disorders (e.g. schizophrenia and mania); anxiety; alcohol or drug withdrawal; pain; gastric stasis; gastric dysfunction (such as occurs with

Method of using a gastrointestinal stimulator device for digestive and eating disorders

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION Gastrointestinal stimulation, or pacing, was advocated as a possible treatment for gastric motor dysfunction as early as 1963. Experimentation in the late 1960s and early 1970s, began to demonstrate the significance of gastrointestinal myoelectrical activity and its

Benzimidazolone carboxylic acid derivatives

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives

Benzimidazolone carboxylic acid derivatives

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives

Benzimidazolone carboxylic acid derivatives

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives

Material and methods for the treatment of gastro-intestinal disorders

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD The present disclosure relates to bulk compositions and pharmaceutical compositions comprising a trihydrate form of (3S, 4R, 3'R)-6-[4-(4-amino-5-chloro-2-methoxy-benzoylamino)-3-methoxy-piperidin-1- -yl]-hexanoic acid 1-azabicyclo[2.2.2]oct-3'-yl ester di-hydrochloride salt, and methods of

Carbazole derivatives and their use as 5HT-induced antagonists

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
This invention relates to heterocyclic compounds, to processes for their preparation, to pharmaceutical compositions containing them and to their medical use. In particular the invention relates to compounds which act upon 5-hydroxytryptamine (5HT) receptors of the type located on terminals of

Carbazole derivatives and their use as 5HT-induced antagonists

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
This invention relates to heterocyclic compounds, to processes for their preparation, to pharmaceutical compositions containing them and to their medical use. In particular the invention relates to compounds which act upon 5-hydroxytryptamine (5-HT) receptors of the type located on terminals of
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