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Leht 1 alates 17 tulemused

Method and compositions for treating tumors having high tyrosinase activity

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FIELD OF THE INVENTION The present invention is directed to methods and compositions for treating tumors and other metastatic diseases exhibiting high tyrosinase and saccharide enzyme activity. The invention is further directed to methods and compositions for treating tumors having high tyrosinase

Nutrient pharmaceutical formulation comprising polyphenols and use in treatment of cancer

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FIELD OF THE INVENTION The present invention relates to a nutrient pharmaceutical formulation and its use for the treatment of cancer. More specifically, the present invention relates to polyphenol containing pharmaceutical formulations having an effective amount of polyphenols for the treatment of

Tea catechins as cancer specific proliferation inhibitors

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1. INTRODUCTION The present invention relates to novel methods and compositions for the treatment of primary and metastatic cancers. These methods and compositions utilize catechins, including but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), and

Tea catechins as cancer specific proliferation inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
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1. INTRODUCTION The present invention relates to novel methods and compositions for the treatment of primary and metastatic cancers. These methods and compositions utilize catechins, including but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), and

Tea catechins in sustained release formulations as cancer specific proliferation inhibitors

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1. INTRODUCTION The present invention relates to novel methods and sustained release compositions which utilize catechins, including but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), and epigallocatechin (EGC), which are found in varying levels in tea
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not Applicable REFERENCE TO SEQUENCE LISTING, A TABLE, OR A COMPUTER PROGRAM LISTING COMPACT DISK APPENDIX Not Applicable BACKGROUND OF THE INVENTION The present invention relates to novel methods and compositions which utilize

Polyphenol inhibition of nucleoside diphosphate kinase-B activity and cancer metastasis

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates generally to the fields of pharmacology and tumor biology. More specifically, the present invention relates to secretion of nucleoside diphosphate kinase (NDPK) from human tumors and the effects of inhibiting

Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer

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1. INTRODUCTION The present invention relates to novel methods and compositions which utilize catechins, including but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), and epigallocatechin (EGC), which are found in varying levels in tea leaves, in

(-)-epigallocatechin gallate derivatives for inhibiting proteasome

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FIELD OF THE INVENTION This invention relates to derivates of (-)-epigallocatechin gallate, particularly for use as proteasome inhibitors and/or for inhibition of cancer cell growth. BACKGROUND OF THE INVENTION The polyphenols found in green tea extracts are (-)-epicatechin (EC),

(-)-Epigallocatechin gallate derivatives for inhibiting proteasome

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FIELD OF THE INVENTION This invention relates to derivates of (-)-epigallocatechin gallate, particularly for use as proteasome inhibitors and/or for inhibition of cancer cell growth. BACKGROUND OF THE INVENTION The polyphenols found in green tea extracts are (-)-epicatechin (EC),
CROSS REFERENCE TO RELATED APPLICATIONS This application is the National Stage of PCT/RU2013/000568 filed on Jul. 19, 2013, which claims priority under 35 U.S.C. .sctn.119 of Russian Application No. 2012144002 filed on Oct. 16, 2012, the disclosures of which are incorporated by reference. The

Method of treating topical angiogenesis-related disorders

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FIELD OF THE INVENTION The invention relates to cosmetic and pharmaceutical treatment methods. More specifically, the invention relates to treatment of angiogenesis-related disorders, particularly skin disorders. BACKGROUND OF THE INVENTION Angiogenesis, which is the process of producing new

Methods and compositions for inhibiting 5.alpha.-reductase activity

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates generally to compounds, compositions and methods regulating the actions of androgens and other steroid hormones by modulating the activity of 5.alpha.-reductase. More particularly, the present invention relates to

Polyphenol coxib combinations and methods

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FIELD OF THE INVENTION The field of the invention is pharmaceutical agents for treatment and chemoprevention of neoplastic diseases. BACKGROUND OF THE INVENTION Green tea extracts and their isolated constituents have been described in numerous reports as antineoplastic agents. For example, U.S. Pat.

Combretastatin A-3 prodrug

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INTRODUCTION The present invention relates generally to the field of antineoplastic agents and more particularly to novel and unexpectedly beneficial methods of synthesizing combretastatin A-3 and thereafter converting combretastatin A-3 into a series of diphosphate prodrugs containing an anion
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