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hypotension/rasvumus
Link salvestatakse lõikelauale
Leht 1 alates 24 tulemused
Alicyclic imidazoles as H3 agents
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FIELD OF THE INVENTION
The present invention is directed to alicyclic imidazoles which interact with the histamine H.sub.3 receptor as agonists, antagonists or inverse agonists; pharmaceutically active compositions containing such compounds; and the use of such compounds in formulations for the
Polynucleotides that encode the calcitonin gene-related peptide receptor coponent factor (HOUNDC44)
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FIELD OF THE INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists
Use of morphine derivatives as medicaments for the treatment of neuropathic problems
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BACKGROUND AND SUMMARY OF THE INVENTION
The present invention relates to the use of morphinan derivatives as well as their bases or salts of physiologically compatible acids as regulators for the nociceptin/orphanin FQ ligand ORL1 receptor system and for the production of a medicament.
The
H.sub.3 receptor ligands of the phenyl-alkyl-imidazoles type
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FIELD OF THE INVENTION
The present invention relates to phenyl-alkyl-imidazoles having valuable pharmacological properties, especially CNS activities and activity against inflammatory disease. Compounds of this invention are antagonists of the H.sub.3 receptor.
BACKGROUND OF THE INVENTION
European
Phenyl-alkyl-imidazoles
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FIELD OF THE INVENTION
The present invention relates to novel phenyl-alkyl-imidazoles having valuable pharmacological properties, especially CNS activities and activity against inflammatory disease. Compounds of this invention are antagonists of the H.sub.3 receptor.
BACKGROUND OF THE
Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom
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BACKGROUND
H.sub.3 receptor sites are known and are of current interest to those skilled in the art--for example, see: West, Jr. et al., "Biexponential Kinetics of (R)-.alpha.-[.sup.3 H]Methylhistamine Binding to the Rat Brain H.sub.3 Histamine Receptor", Journal of Neurochemistry, Vol. 55, No. 5,
Histamine-3 receptor antagonists
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BACKGROUND OF THE INVENTION
This invention is directed to compounds of formula I described herein, to a pharmaceutical composition comprising such compounds, and to methods of treatment of disorders or conditions that may be treated by antagonizing histamine-3 (H3) receptors using such compounds.
Histamine-3 receptor modulators
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The entire disclosure of parent application 60/541,151 filed Feb. 2, 2004 is fully incorporated herein by reference thereto.
BACKGROUND OF THE INVENTION
This invention is directed to compounds of formula I described herein, to pharmaceutical composition comprising such compounds, and to methods of
Histamine-3 receptor antagonists
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BACKGROUND OF THE INVENTION
This invention is directed to compounds of formula I described herein, to a pharmaceutical composition comprising such compounds, to a process of preparation of such compounds, and to methods of treatment of disorders or conditions that may be treated by antagonizing
Histamine-3 receptor antagonists
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BACKGROUND OF THE INVENTION
This invention is directed to compounds of formula I described herein, to a pharmaceutical composition comprising such compounds, to a process of preparation of such compounds, and to methods of treatment of disorders or conditions that may be treated by antagonizing
Methods of screening for agonists and antagonists of the interaction between the human KIAA0001 receptor and ligands thereof
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FIELD OF THE INVENTION
This invention relates to methods for discovering agonists and antagonists of the interaction between UDP-sugars (e.g.,UDP-glucose, UDP-galactose, UDP-glucuronic acid, and UDP-N-acetyl glucosamine) and their cellular receptor, human KIAA0001 receptor. The invention also
Toluene sulfonic acid salt of a therapeutic compound and pharmaceutical compositions thereof
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The present invention is directed to the tosylate salt of the compound of formula 1, as described herein, to a pharmaceutical composition comprising this salt, and to methods of treatment of disorders or conditions that may be treated by antagonizing histamine-3 (H.sub.3) receptors using the
Sulphonamide derivatives, their preparation and their therapeutic application
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FIELD OF THE INVENTION
The present invention relates to sulfonamide derivatives, to the process for preparing them and to their therapeutic use.
BACKGROUND OF THE INVENTION
Orexins A and B (or hypocretins 1 and 2) are hypothalamus neuropeptides of 33 and 28 amino acids, respectively, recently
Human 7-TM receptor similar to murine frizzled-6 gene
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FIELD OF INVENTION
This invention relates to newly identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to G-protein coupled
Polynucleotides encoding MY1 receptor
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FIELD OF INVENTION
This invention relates to newly identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More articularly, the polynucleotides and polypeptides of the present invention relate to G-protein coupled
Kõige täiuslikum ravimtaimede andmebaas, mida toetab teadus
- Töötab 55 keeles
- Taimsed ravimid, mida toetab teadus
- Maitsetaimede äratundmine pildi järgi
- Interaktiivne GPS-kaart - märgistage ürdid asukohas (varsti)
- Lugege oma otsinguga seotud teaduspublikatsioone
- Otsige ravimtaimi nende mõju järgi
- Korraldage oma huvisid ja hoidke end kursis uudisteuuringute, kliiniliste uuringute ja patentidega
Sisestage sümptom või haigus ja lugege ravimtaimede kohta, mis võivad aidata, tippige ürdi ja vaadake haigusi ja sümptomeid, mille vastu seda kasutatakse.
* Kogu teave põhineb avaldatud teaduslikel uuringutel
