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inflammation/iiveldus

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Leht 1 alates 21 tulemused

Analgesic and anti-inflammatory compositions comprising domperidone and methods of using same

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Logi sisse
BACKGROUND TO THE ART The current means of combating migraine attacks include simple analgesics such as aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDS) and paracetamol, taken at the earliest signs of an attack [1,2,3]. Aspirin, paracetamol and phenacetin have long been among the most

Modulation of substance P by compounds containing calcium sulfate and methods relating thereto

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TECHNICAL FIELD The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions

Method for pain relief using low power laser light

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Logi sisse
BACKGROUND OF THE INVENTION Although it is often said that the common cold is the most prevalent disease among humankind, it is also true that chronic pain is an affliction that is almost as prevalent. Chronic headaches, muscle pain, joint pain, and the like are experienced by most individuals, and

ABHD6 and dual ABHD6/MGL inhibitors and their uses

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Logi sisse
BACKGROUND Cannabinoid receptors, CB1 and CB2, are part of the endocannabinoid system (ECS), which consists of cannabinoid receptors, endogenous endocannabinoids anandamide (AEA) and 2-arachindonoylglycerol (2-AG) and the hydrolytic enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol

Treatment of the acute after-effects resulting from alcohol ingestion

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Logi sisse
This invention relates to the prevention of the acute post-alcoholic intoxication state, commonly called the alcohol "hangover". A "hangover" results from ingesting a relatively excessive quantity of alcohol, a term understood to refer to alcoholic beverages as well as any particular alcohol found

Amines that inhibit a mammalian anandamide transporter, and methods of use thereof

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Logi sisse
BACKGROUND OF THE INVENTION Mammalian Endogenous Cannabinoid System The various elements of the mammalian endogenous cannabinoid system (ECS) constitute a variety of pharmacological targets for the broad group of compounds generally termed as cannabinoids. Included among these elements are two types

Amines that inhibit a mammalian anandamide transporter, and methods of use thereof

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION Mammalian Endogenous Cannabinoid System The various elements of the mammalian endogenous cannabinoid system (ECS) constitute a variety of pharmacological targets for the broad group of compounds generally termed as cannabinoids. Included among these elements are two types

Amines that inhibit a mammalian anandamide transporter, and methods of use thereof

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION Mammalian Endogenous Cannabinoid System The various elements of the mammalian endogenous cannabinoid system (ECS) constitute a variety of pharmacological targets for the broad group of compounds generally termed as cannabinoids. Included among these elements are two types

Bisarylimidazolyl fatty acid amide hydrolase inhibitors

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Logi sisse
FIELD OF THE INVENTION The present invention relates to bisarylimidazolyl derivatives and pharmaceutical compositions comprising said derivatives which inhibit fatty acid amide hydrolase and are useful for the treatment of conditions affected by inhibiting fatty acid amide

Treatment of emesis with morpholine tachykinin receptor antagonists

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Logi sisse
SUMMARY OF THE INVENTION This invention is concerned with novel compounds represented by structural formula I: ##STR2## wherein R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, B, p, Y and Z are hereinafter defined. The invention is also concerned with pharmaceutical

Treatment of migraine with morpholine tachykinin receptor antagonists

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
SUMMARY OF THE INVENTION This invention is concerned with novel compounds represented by structural formula I: ##STR2## wherein R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, B, p, Y and Z are hereinafter defined. The invention is also concerned with pharmaceutical

Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders

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FIELD OF THE INVENTION The present invention relates to novel conformationally-defined macrocyclic compounds that bind to and/or are functional modulators of the motilin receptor including subtypes, isoforms and/or variants thereof. These macrocyclic compounds possess appropriate pharmacological

Urea compounds and their use as enzyme inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty

Urea compounds and their use as enzyme inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty
FIELD OF THE INVENTION This invention relates to the use of a composition containing extracts of Buddleja globosa Hope and pharmacologically accepted additives for the treatment or prevention of several gastrointestinal disorders, particularly those associated with patient treatment with
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