Potassium citrate x 7days Off therapy x 7 days 500 mL low calorie orange juice beverage x 7 days 1000 mL low calorie orange juice beverage x 7 days Return to potassium citrate therapy Litholink urine collection to be performed after each 7 days treatment

500 mL low calorie orange juice beverage x 7 days 1000 mL low calorie orange juice beverage x 7 days Off therapy x 7 days Potassium citrate x 7days Continue on potassium citrate therapy Litholink urine collection to be performed after each 7 days treatment

Kidney Calculi

Kroger low calorie orange juice beverage will be consumed for 7 days followed by a 24 hour urine collection with Litholink to see if urine alkalization similar to potassium citrate can be achieved

Kroger low calorie orange juice beverage

Indiana University Health Methodist Hospital

Indiana University Health Physicians Urology

A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kidney Stones

A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With a History of Nephrolithiasis

The primary endpoint of interest will be the changes in urinary citrate while consuming Kroger low calorie orange juice beverage compared to potassium citrate therapy.

The primary endpoint of interest will be the changes in urinary pH while consuming Kroger low calorie orange juice beverage compared to potassium citrate therapy.

Tim Large

Principal Investigator

Indiana University

Group 1 kcit x 7 days ↓ Litholink on day 7
↓ off therapy x 7 days
↓ OJ 500 ML + 1.5L water /day x 7 days
↓ Litholink on day 7
↓ OJ 1000 ML + 1L water /day x 7 days
↓ Litholink on day 7 Return to kcit therapy
Group 2 OJ 500 ML + 1.5L water /day x 7 days ↓ Litholink on day 7
↓ OJ 1000 ML + 1L water /day x 7 days
↓ Litholink on day 7
↓ off therapy x 7 days
↓ kcit x 7 days
↓ Litholink on day 7 Continue on kcit therapy

Diet modification - nortriptyline and then if necessary topiramate

Diet Modification topiramate and then nortriptyline if necessary

Migraine Disorders

The nortriptyline will be given in an escalating fashion, starting at 25 mg PO qhs for 2 weeks, followed by 50 mg PO qhs for 2 weeks, and finally 75 mg PO qhs. Patients will be encouraged to use the lowest effective dose and to self-titrate their medication.

nortriptyline

Topiramate dosing will be 25 mg PO qhs for 1 week, followed by 25 mg BID for 1 week, followed by 25 mg in the morning and 50 mg qhs for 1 week, and finally 50 mg BID

Topiramate

Saint Louis University

Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine

A Prospective Randomized Cross-over Trial of Nortryptyline and Topiramate in the Initial Treatment of Vestibular Migraine.

Changes in Migraine Specific Quality of LIfe (MSQ) and Dizziness Handicap Inventory (DHI) between groups

Anthony A. Mikulec, MD

Associate Professor

St. Louis University

Patients will receive ESWL and no medication

Patients will receive silodosin after ESWL

Kidney Stones

silodosin

Extra-corporeal shock wave lithotripsy

Tamsulosin

Albert Einstein Healthcare Network

Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy

Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After ESWL

The primary endpoint of this study is the clearance rate of kidney stones. That is, in what period of time does the patient achieve clearance, is stone free and has all residual stones gone. This outcome measure will be measured in days.

Analgesic use, number of pills of pain medication

Residual stones remaining, based on imaging

need for re-treatment. Either the patient will need another ESWL, or hospitilization

need for intervention. Either ESWL again or hospitilization and further procedures such as laser lithotripsy, percutaneous nephrolithotomy, open surgery

kidney calculi/peavalu

A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kidney Stones

Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine

Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy

Kõige täiuslikum ravimtaimede andmebaas, mida toetab teadus