H Pylori Infection

Screening of Helicobacter Pylori in Children of Positive Infected Mothers

Screening of Helicobacter Pylori Infection in Children of Positive Infected Mothers

By taken children whose mother infected ,how many of them infected by this microbe by taken these child and done the following investigastion as stool antigen test and biobsy if they are postive by test and then follow up by treatment

By knowing effect of this microbe on growth development of children by measure weigt /height through body mass index and measure heamoglbin level
By taken children whose positive H pylori follow effect of this microbe on heamoglbin level and do investigation as complete blood count By following test such as complete blood count and heamoglbin level and if this microbe increase level of anemia or not

Samaa Sayed

Principle investigator

Assiut University

Patients receive both mucosal buccal biopsy and insertion of cell sheets during/after ESD/EMR

patients receive both mucosal biopsy but no placement of cell sheets during/after ESD

Barrett Esophagus

Patients receive ESD/EMR plus CellSheet:
Autologous oral mucosa/buccal-derived epithelial cells, cultured on temperature-sensitive membrane ("Cell Sheet") that are inserted 2 weeks later on the occasion of the ESD or EMR

ESD/EMR plus Cell Sheet

only ESD/EMR: Autologous oral mucosa/buccal-derived epithelial cells, cultured on temperature-sensitive membrane ("Cell Sheet") but NOT used for insertion in the patient during/after ESD/EMR two weeks later

ESD/EMR

Gastrocentrum, KarolinskaUniversity Hospital

Autologous Cell Sheets Transplantation After ESD in the Esophagus

Transplantation of Autologous Cell Sheets After Endoscopic Submucosal Dissection (ESD) for Early Adenocarcinoma of the Esophagus

Development of an oesophageal stenosis that cannot be passed by a standard 9 mm endoscope

Matthias Löhr

Professor of Gastroenterology & Herpetology

Pomalidomide: Comparison of different dosages and schedules of drug

Pomalidomide 2 mg/d on 28 Days/28 Day Cycle

Pomalidomide 4 mg/d on 21 Days/28 Day Cycle

Total

Sex: Female, Male

Immunoglobulin Heavy chain (IgH) type

Immunoglobulin Light chain (IgL) type

serum beta 2 microglobulin

serum albumin

lines of prior therapy

Deletion of chromosome 17p

Chromosome 1q abnormalities

Monosomy 13 on molecular cytogenics or deletion of 13q on fluorescence in situ hybridization (FISH) cytogenics

Deletion chromosome 13

Lenalidomide (Len) as most recent therapy

Resistance to prior therapy-Len refractory

Resistance to prior therapy-Len+bortezomib refractory

All partial and complete responses must be confirmed with another efficacy assessment in no less than 4 weeks apart.

Percentage of Participants With Response, Analyzed Per International Myeloma Working Group Response Criteria

Correlation to be determined upon completion of study treatment

To Compare the Effect of Continuous Versus Intermittent Regimens on F Actin Polymerization in Peripheral Blood Mononuclear Cells and Activation of Tumor Antigen-specific T Cells, as Well as Innate Lymphocytes (Natural Killer or Natural Killer T Cells).

Research bone marrow aspirate is obtained to assess response (optional, but recommended), and to document complete remission, if applicable. Correlation to be determined upon completion of study treatment

To Correlate Drug Induced Changes in F Actin Polymerization With Adverse Effects and Clinical Responses.

To Correlate Drug Induced Changes in F Actin With Cytokine Profile.

Overall Study

Madhav Dhodapkar, M.D.

Multiple Myeloma

Comparison of different dosages and schedules of drug

metaplasia/diarrhea

Screening of Helicobacter Pylori in Children of Positive Infected Mothers

Autologous Cell Sheets Transplantation After ESD in the Esophagus

Continuous Versus Intermittent Dosing Regimens for Pomalidomide in Relapsed/Refractory Multiple Myeloma

Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder

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